PureCube MagBeads | Cube Biotech

Magnetic Beads


MagBeads
We produce and use our own PureCube MagBeads. With a ferrimagnetic core and an agarose coating coupled to a ligand of choice, their surface is identical to our PureCube Agarose matrices, making them an ideal combination for all purification scales. In addition, the amount of magnetic beads used for a purification setup can be easily scaled up and down to match protein expression rates and culture volumes. Available volumes range from 1 ml to bulk scale at affordable pricing.

PureCube MagBeads are useful to:

  • extract proteins from diluted solutions, such as cell culture supernatants
  • purify proteins expressed at low levels
  • perform pull-down experiments
  • automate small-scale protein purification
A modular MagBead separator for 1.5 and 2 ml tubes is available. For consistent separation of the magnetic beads in larger scale, we recommend Sepmag homogeneous biomagnetic separation systems.

HIS
The His tag is the most widely used affinity tag because of its small size (6-10 aa) and ease of use. His-tag affinity purification can be performed under native and denaturing conditions and tolerates a wide range of detergents and other additives. A range of different His affinity magbeads is available:
Ni-INDIGONi-NTANi-IDACo-NTAIDANTAOther Metals

GST
The GST tag is a 26 kDa protein tag which is often chosen to promote recombinant protein folding.

Strep
The Strep-tag® is a 8 amino acid tag with high specificity for StrepTactin® magbeads which is often used as alternative or in combination with the His tag

Rho
The rho1D4-tag is a 9 amino acid tag that binds to the rho1D4 antibody and has proven particularly efficient in the purification of membrane proteins. For the first time commercially available, Cube Biotech offers the full system (affinity magbeads, rho1D4 peptide, and rho1D4 antibody).

Activated
Activated MagBeads can be used to couple your own antibody or other molecule to create a protein-specific affinity matrix. Available modifications include:

IEX
For untagged proteins, or as additional purification step, ion exchange magbeads can be used. Please contact us for more information.

XL
Extra-large magbeads can be used for a combination of magnetic and filter separation during purification, and for other special applications.

Custom Button
Special and Custom Matrices can be used for tag-free purification, purification of native proteins and specific protein conformations. Learn more.

StrepTactin® and Strep-tag® are trademarks of IBA GmbH.
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Magnetic Beads
MagBeads
We produce and use our own PureCube MagBeads. With a ferrimagnetic core and an agarose coating coupled to a ligand of choice, their surface is identical to our PureCube Agarose matrices, making them an ideal combination for all purification scales. In addition, the amount of magnetic beads used for a purification setup can be easily scaled up and down to match protein expression rates and culture volumes. Available volumes range from 1 ml to bulk scale at affordable pricing.

PureCube MagBeads are useful to:

  • extract proteins from diluted solutions, such as cell culture supernatants
  • purify proteins expressed at low levels
  • perform pull-down experiments
  • automate small-scale protein purification
A modular MagBead separator for 1.5 and 2 ml tubes is available. For consistent separation of the magnetic beads in larger scale, we recommend Sepmag homogeneous biomagnetic separation systems.

HIS
The His tag is the most widely used affinity tag because of its small size (6-10 aa) and ease of use. His-tag affinity purification can be performed under native and denaturing conditions and tolerates a wide range of detergents and other additives. A range of different His affinity magbeads is available:
Ni-INDIGONi-NTANi-IDACo-NTAIDANTAOther Metals

GST
The GST tag is a 26 kDa protein tag which is often chosen to promote recombinant protein folding.

Strep
The Strep-tag® is a 8 amino acid tag with high specificity for StrepTactin® magbeads which is often used as alternative or in combination with the His tag

Rho
The rho1D4-tag is a 9 amino acid tag that binds to the rho1D4 antibody and has proven particularly efficient in the purification of membrane proteins. For the first time commercially available, Cube Biotech offers the full system (affinity magbeads, rho1D4 peptide, and rho1D4 antibody).

Activated
Activated MagBeads can be used to couple your own antibody or other molecule to create a protein-specific affinity matrix. Available modifications include:

IEX
For untagged proteins, or as additional purification step, ion exchange magbeads can be used. Please contact us for more information.

XL
Extra-large magbeads can be used for a combination of magnetic and filter separation during purification, and for other special applications.

Custom Button
Special and Custom Matrices can be used for tag-free purification, purification of native proteins and specific protein conformations. Learn more.

StrepTactin® and Strep-tag® are trademarks of IBA GmbH.
Magnetic Beads
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PureCube Glutathione MagBeads PureCube Glutathione MagBeads
1 ml 25% Glutathione Magnetic Beads For more information read here: https://cube-biotech.com/products/magnetic-beads/gst-affinity-magbeads/#
Article number: 32201
Sales price: From €49.00 *
PureCube Fe-NTA MagBeads PureCube Fe-NTA MagBeads
1 ml 25% NTA magnetic beads, loaded with iron (III) chloride
Article number: 31501-Fe
Sales price: From €66.00 *
PureCube INDIGO Ni-MagBeads PureCube INDIGO Ni-MagBeads
1 ml 25% magnetic beads equipped with a proprietary ligand for His affinity purification, loaded with nickel (II) sulfate For more information read here: https://cube-biotech.com/products/magnetic-beads/his-affinity-magbeads/#
Article number: 75201
Sales price: From €67.00 *
PureCube HiCap StrepTactin MagBeads PureCube HiCap StrepTactin MagBeads
1 ml 5% High Capacity StrepTactin Magnetic Beads  
Article number: 34201
Sales price: From €76.00 *
PureCube Ni-NTA Mag Beads PureCube Ni-NTA Mag Beads
1 ml 25% NTA magnetic beads, loaded with nickel (II) sulfate
Article number: 31201
Sales price: From €61.00 *
PureCube Epoxy Activated MagBeads PureCube Epoxy Activated MagBeads
Lyophilized resin for 1 ml 25% Epoxy activated Magnetic Beads suspension ►For coupling of biomolecules via amine or thiol groups
Article number: 50801
Sales price: From €95.00 *
PureCube Amine Activated MagBeads PureCube Amine Activated MagBeads
1 ml 25% Amine-Activated MagBeads, for coupling of biomolecules via carboxy groups using EDC/NHS
Article number: 50901
Sales price: From €97.00 *
PureCube Maleimide Activated MagBeads PureCube Maleimide Activated MagBeads
1 ml 25% Maleimide-Activated MagBeads, for direct, irreversible coupling of biomolecules via thiol groups  
Article number: 51201
Sales price: From €135.00 *
Cube MagBead Separator (1) Cube MagBead Separator (1)
1 Cube MagBead Separator, for 2 microtubes of 1.5 or 2 ml volume.
Article number: 16941
Sales price: From €61.00 *
PureCube Co-NTA MagBeads PureCube Co-NTA MagBeads
1 ml 25% NTA magnetic beads, loaded with cobalt (II) chloride
Article number: 31501
Sales price: From €66.00 *
PureCube Rho1D4 MagBeads PureCube Rho1D4 MagBeads
1 ml 5% Rho1D4 Magnetic Beads
Article number: 33201
Sales price: From €241.00 *
Rho Starter Set 2: PureCube Rho1D4 MagBeads (1 ml) + Rho1D4 peptide (5 mg) Rho Starter Set 2: PureCube Rho1D4 MagBeads (1...
Set of 1 ml 5% Rho1D4 MagBeads and 5 mg lyophilized Rho1D4 peptide. Provides a 50% discount compared to purchase of individual items.
Article number: 33299
Sales price: €173.00 *
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