Synthetic nanodisc products



Synthetic nanodiscs are the most flexible approach to solubilize & stabilize membrane proteins. Their greatest advantage lies in the fact that they stabilize the membrane protein in its native lipid environment.

If you would like to know more about synthetic nanodiscs have a look at our "What are nanodiscs?" page.
Currently these are our options for the creation of synthetic nanodiscs:

Unsure which polymer to choose? Simply use our Screening Kits for your first attempts on a new protein.


Have a look at our Membrane Protein Solubilization Database to see solubilization data of your membrane protein already exist.


Comparison between the individual polymer's key features.

PolymerMolecular WeightAbsorbance
at 280 nm
pH after dissolvingMg2+ toleranceCa2+ tolerance
DIBMA 10-12 kDa minimal <0,3
(1% in solution)
7.5 25 mM to over 50 mM >50 mM
SMA 5-10 kDa Yes 7.5 - 8.0 4 mM to 100 mM 4 mM to 100 mM
AASTY 5-10 kDa Yes 7.5 - 8.0 6 mM - 20 mM 6 mM
Ultrasolute™ Amphipols 7-8 kDa No (below 0.1) 7.5 ± 0.3 Not determined yet Not determined yet
 
Synthetic nanodisc products
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SMALP 200 SMALP 200
Our SMALP polymer products are made to provide an easy way to stabilize and solubilize membrane proteins.
Article number: 18210
Sales price: From €209.00 *
Overview of all Synthetic polymers that are contained in the MAXI screening Kit Synthetic Nanodisc Screening Kit MAXI (16x2x50 mg)
Not sure what type of synthetic nanodisc is best for your membrane protein? Use our MAXI screening kit to find out.
Article number: 18295
Sales price: €650.00 *
Synthetic Nanodisc Screening Kit MINI, (8x2x50 mg) Synthetic Nanodisc Screening Kit MINI, (8x2x50 mg)
Not sure if SMA or DIBMA make the best nanodiscs for your protein? Why not try both!
Article number: 18290
Sales price: €360.00 *
Tube containing Ultrasolute™ Amphipol 18 Ultrasolute™ Amphipol 18 HEPES
The new Ultrasolute™ Amphipol 18 for your membrane protein assays. Amphipols are now better than ever before!
Article number: 18321
Sales price: From €209.00 *
SMALP 140-I SMALP 140-I
Our SMALP polymer products are made to provide an easy way to stabilize and solubilize membrane proteins.
Article number: 18230
Sales price: From €209.00 *
DIBMA Screening Kit, HEPES (4x3x50 mg) DIBMA Screening Kit, HEPES (4x3x50 mg)
Unsure which DIBMA is best suited for your membrane protein experiments? Use our DIBMA HEPES Screening Set to find out.
Article number: 18101
Sales price: €231.00 *
DIBMA Screening Kit, TRIS (4x3x50 mg) DIBMA Screening Kit, TRIS (4x3x50 mg)
Unsure which DIBMA is best suited for your membrane protein experiments? Use our TRIS Screening Set to find out.
Article number: 18104
Sales price: €231.00 *
Vial containing DIBMA 12 HEPES DIBMA 12, HEPES
PureCube DIBMA by Cube-Biotech. For protein solubilization. | Amount=1 gramm | Buffered in TRIS. | MW=12.000 g/mol
Article number: 18011
Sales price: From €209.00 *
Vial containing DIBMA 12 TRIS DIBMA 12, TRIS
PureCube DIBMA by Cube-Biotech. For protein solubilization. | Amount=1 gramm | Buffered in TRIS. | MW=12.000 g/mol
Article number: 18014
Sales price: From €209.00 *
Vial containing DIBMA 10 Tris DIBMA 10, TRIS
PureCube DIBMA by Cube-Biotech. For protein solubilization. | Amount=1 gramm | Buffered in TRIS. | MW=10.000 g/mol
Article number: 18004
Sales price: From €209.00 *
Tube containing DIBMA Glucosamine TRIS DIBMA Glucosamine, TRIS
Cube Biotech offers DIBMA-Glucosamine for reduced net charge of the polymer. Higher ion tollerance for your experiments.
Article number: 18044
Sales price: From €229.00 *
Tube Containing DIBMA Glycerol TRIS DIBMA Glycerol, TRIS
Cube Biotech offers DIBMA-Glycerol for reduced net charge of the polymer. Higher ion tollerance for your experiments.
Article number: 18054
Sales price: From €229.00 *
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