Synthetic nanodisc products



Synthetic nanodiscs are the most flexible approach to solubilize & stabilize membrane proteins. Their greatest advantage lies in the fact that they stabilize the membrane protein in its native lipid environment.

If you would like to know more about synthetic nanodiscs have a look at our "What are nanodiscs?" page.
Currently these are our options for the creation of synthetic nanodiscs:

Unsure which polymer to choose? Simply use our Screening Kits for your first attempts on a new protein.


Have a look at our Membrane Protein Solubilization Database to see solubilization data of your membrane protein already exist.


Comparison between the individual polymer's key features.

PolymerMolecular WeightAbsorbance
at 280 nm
pH after dissolvingMg2+ toleranceCa2+ tolerance
DIBMA 10-12 kDa minimal <0,3
(1% in solution)
7.5 25 mM to over 50 mM >50 mM
SMA 5-10 kDa Yes 7.5 - 8.0 4 mM to 100 mM 4 mM to 100 mM
AASTY 5-10 kDa Yes 7.5 - 8.0 6mM - 20 mM 6mM
Ultrasolute™ Amphipols 7-8 kDa No (below 0.1) 7.5 ± 0.3 Not determined yet Not determined yet
 
Top seller
SMALP 200 SMALP 200
Article number: 18210
SMALP 300 SMALP 300
Article number: 18200
AASTY 6-45 by Cube Biotech AASTY 6-45
Article number: 18250
Vial containing DIBMA 12 TRIS DIBMA 12, TRIS
Article number: 18014
Synthetic nanodisc products
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Synthetic Nanodisc Screening Kit MINI, (8x2x50 mg) Synthetic Nanodisc Screening Kit MINI, (8x2x50 mg)
Not sure if SMA or DIBMA make the best nanodiscs for your protein? Why not try both!
Article number: 18290
Sales price: €360.00 *
SMALP Screening Set (4x3x50 mg) SMALP Screening Set (4x3x50 mg)
Article number: 18280
Sales price: €291.00 *
SMALP 200 SMALP 200
Our SMALP polymer products are made to provide an easy way to stabilize and solubilize membrane proteins.
Article number: 18210
Sales price: From €209.00 *
AASTY Screening Kit Contents AASTY Screening Kit (6x2x50 mg)
Not sure which AASTY fits your membrane protein the best? Our AASTY Screening Kit exists to answer this question!
Article number: 18285
Sales price: €231.00 *
SMALP 300 SMALP 300
Our SMALP polymer products are made to provide an easy way to stabilize and solubilize membrane proteins.
Article number: 18200
Sales price: From €209.00 *
Overview of all Synthetic polymers that are contained in the MAXI screening Kit Synthetic Nanodisc Screening Kit MAXI (16x2x50 mg)
Not sure what type of synthetic nanodisc is best for your membrane protein? Use our MAXI screening kit to find out.
Article number: 18295
Sales price: €650.00 *
AASTY 6-45 by Cube Biotech AASTY 6-45
AASTY 6-45 is the one of the more aggressive polymers for membrane proteins stabilization. Find out more!
Article number: 18250
Sales price: From €209.00 *
Vial containing DIBMA 12 TRIS DIBMA 12, TRIS
PureCube DIBMA by Cube-Biotech. For protein solubilization. | Amount=1 gramm | Buffered in TRIS. | MW=12.000 g/mol
Article number: 18014
Sales price: From €209.00 *
Tube containing Ultrasolute™ Amphipol 18 Ultrasolute™ Amphipol 18 HEPES
The new Ultrasolute™ Amphipol 18 for your membrane protein assays. Amphipols are now better than ever before!
Article number: 18321
Sales price: From €209.00 *
DIBMA Screening Kit, TRIS (4x3x50 mg) DIBMA Screening Kit, TRIS (4x3x50 mg)
Unsure which DIBMA is best suited for your membrane protein experiments? Use our TRIS Screening Set to find out.
Article number: 18104
Sales price: €231.00 *
Vial containing DIBMA 12 HEPES DIBMA 12, HEPES
PureCube DIBMA by Cube-Biotech. For protein solubilization. | Amount=1 gramm | Buffered in TRIS. | MW=12.000 g/mol
Article number: 18011
Sales price: From €209.00 *
Tube containing DIBMA 10 HEPES DIBMA 10, HEPES
PureCube DIBMA by Cube-Biotech. For protein solubilization. | Amount = 10x50mg | Buffered in HEPES. | MW=10.000 g/mol
Article number: 18001
Sales price: From €209.00 *
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