Glyco-DIBMA

€229.00 *

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Glyco-DIBMA is a modified version of DIBMA with an added sugar side-chain to the polymer... more
Product information "Glyco-DIBMA"
Glyco-DIBMA is a modified version of DIBMA with an added sugar side-chain to the polymer molecule. Its purpose is to enhance DIBMA's range for solubilizing membrane proteins.

After solving the Glyco-DIBMA + buffer powder in water, the product is ready-to-use. It can primarily be used for all cell membrane hosts, including bacteria, yeast and human cells.

After successful solubilization of the membrane protein of interest, the protein can be purified using affinity chromatography. We recommend the Rho1D4-tag for membrane protein purification and offer matching products for this purpose.

DIBMA / Nanodisc Screening:  Each membrane protein may perform better or differently with certain synthetic polymers. This is due to the characteristic composition of phospholipids surrounding the membrane proteins. Therefore a screening process for the correct DIBMA/polymer is required in before.
For this purpose we offer our synthetic nanodisc screening kit MAXI that contains DIBMA, AASTY and SMA.

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Features

State Lyophilized Powder,
to be solved with water
Molecular weight 15701 g/Mol
pH after solving 7.5
Solubility >10%
Divalent cationic tolerance < 4 mM
Adsorbance (280 nm, 1% solution) > 0.3
Buffer HEPES
Specific gravity 1.1
Storage 4°C for long-term
Structure Glyco-DIBMA Structure

Our protocol video that shows a full solubilization process using DIBMA and other synthetic polymers

 
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