Synthetic Nanodisc Screening Kit MINI, (8x2x50 mg)

Finding the best performing synthetic nanodisc polymer for your respective nanodisc can be tricky. Especially if you have never worked with your current membrane protein of interest before. For these cases we at Cube Biotech compiled our most prominent SMALP and DIBMA products into this practical Synthetic Nanodisc Screening Set for your convenience!
All 8 products are buffered in HEPES to provide maximal comparability between the individual screening assays. Which 8 products are include in the Kit precisely can be found in the product's description.

Figure 1 shows the necessity for a SMALP screen instead of using a random SMALP product. Note that the detergent LMNG may provide the mighest protein yield, but it has to be added to the purified protein constantly and it might interfere with the SPIKE protein's function.

Included SMALP Products

Feature	SMALP 140	SMALP 140-I	SMALP 200	SMALP 300
Polymer styrene-to-maleic-anhydride ratio [n:m]	1.4:1	1.4:1	2:1	3:1
Molecular weight	5,000 Da	5,000 Da	6,500 Da	10,000 Da
Form	Lyophilized powder	Lyophilized powder	Lyophilized powder	Lyophilized powder
pH, after solving	7.5	7.5	7.5	7.5
Divalent cationic tolerance	< 5 mM	< 100 mM	< 5 mM	< 5 mM
Color	Amber	Brownish	Yellowish	Colorless
Odor	Odorless	Odorless	Odorless	Odorless
Other noteworthy feature		is imidized with DMAPA	Most commonly used SMA