SMALP 300
- Order number: 18200
Note: On October 1st 2021 this product was renamed from "SMALP 25010S" to "SMALP... more
Product information "SMALP 300"
Note: On October 1st 2021 this product was renamed from "SMALP 25010S" to "SMALP 300". Nothing else has changed. More on this renaming can be found here:
The SMALP products have been developed for biomedical purposes, in particular, for the solubilization of (biological) lipid membranes and isolation & purification of integral membrane proteins.
After solving the SMA + buffer powder in water, the product is ready-to-use. It can primarily used for all cell membrane hosts, including bacteria, yeast and human cells.
After successfull solubilization of the membrane protein of interest, the protein can be purified using affinity chromatography. We recommend the Rho1D4-tag for membrane protein purification and offer matching products for this purpose.
SMALP Screening: Different membrane protein may perform better with different SMAs variants. To ease your screening process we compiled all of our SMAs into a convenient SMALP Screening Set.
If you also like to compare SMA to DIBMA in the formation of your synthetic nanodiscs, we also offer our, that combines both our SMA and DIBMA products.
After solving the SMA + buffer powder in water, the product is ready-to-use. It can primarily used for all cell membrane hosts, including bacteria, yeast and human cells.
After successfull solubilization of the membrane protein of interest, the protein can be purified using affinity chromatography. We recommend the Rho1D4-tag for membrane protein purification and offer matching products for this purpose.
SMALP Screening: Different membrane protein may perform better with different SMAs variants. To ease your screening process we compiled all of our SMAs into a convenient SMALP Screening Set.
If you also like to compare SMA to DIBMA in the formation of your synthetic nanodiscs, we also offer our, that combines both our SMA and DIBMA products.
Features
| State | Lyophilized Powder, to be solved with water |
| Polymer styrene-to-maleic anhydride ratio | 3:1 |
| Molecular weight | 10.000 |
| pH after solving | 7.5 |
| Solubility | 35% |
| Divalent cationic tolerance | < 5 mM |
| Color | Colorless |
| Odor | Odorless |
| Freeze-thaw stable? | Yes |
| Storage | 4°C for long-term |
| Structure |  |
Figure 1: Western Blot of a purified membrane protein after stabilization through SMA. Reproduced with permission from Ms S. Nestorow, University of Birmingham.
Our protocol video that shows a full solubilization process using SMALP
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