
- Order number: 18280
Note: On October 1st 2021 all SMALP products in this kit were renamed. Nothing else... more
Product information "SMALP Screening Set (4x3x50 mg)"
Note: On October 1st 2021 all SMALP products in this kit were renamed. Nothing else has changed. More on this renaming can be found here:
Membrane protein and their composition as as versatile as the whole cell membrane itself. For this reason it is sadly impossible to predict with a 100% accuracy which SMALP product is suited best for the solubilization & subsequent of your membrane protein of interest.
For this reason we offer this SMALP Screening Kit that consists of our four individual SMAs. This way you have a convenient way to screen for the best SMA for your protein before scaling up your assay.
In case you would like to extend your polymer screening beyond the reaches of SMA we offer our Synthetic Nanodisc Screening Kit, that covers both SMA and DIBMA.
Figure 1 shows the necessity for a SMALP screen instead of using a random SMALP product. Note that the detergent LMNG may provide the mighest protein yield, but it has to be added to the purified protein constantly and it might interfere with the SPIKE protein's function.
For this reason we offer this SMALP Screening Kit that consists of our four individual SMAs. This way you have a convenient way to screen for the best SMA for your protein before scaling up your assay.
In case you would like to extend your polymer screening beyond the reaches of SMA we offer our Synthetic Nanodisc Screening Kit, that covers both SMA and DIBMA.
Figure 1 shows the necessity for a SMALP screen instead of using a random SMALP product. Note that the detergent LMNG may provide the mighest protein yield, but it has to be added to the purified protein constantly and it might interfere with the SPIKE protein's function.

Our SMALP Screening Set consits off the following four individual products:
Feature | SMALP 140 | SMALP 140-I | SMALP 200 | SMALP 300 |
Polymer styrene-to-maleic-anhydride ratio [n:m] | 1.4:1 | 1.4:1 | 2:1 | 3:1 |
Molecular weight | 5,000 Da | 5,000 Da | 6,500 Da | 10,000 Da |
Form | Lyophilized powder | Lyophilized powder | Lyophilized powder | Lyophilized powder |
pH, after solving | 7.5 | 7.5 | 7.5 | 7.5 |
Divalent cationic tolerance | < 5 mM | < 100 mM | < 5 mM | < 5 mM |
Color | Amber | Brownish | Yellowish | Colorless |
Odor | Odorless | Odorless | Odorless | Odorless |
Other noteworthy feature | is imidized with DMAPA | Most commonly used SMA |
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