Protein Purification Products


Purification Resins
Once expressed proteins are extracted from cell lysates or membranes, affinity chromatography is an elegant way to purify these to homogeneity in very few steps. There are multiple ways to gain this homogeneity, but mostly affinity tags are used together with a matching purification resin. Cube Biotech offers a broad range of purification agarose resins or magnetic beads for the purification of functional protein. See below what types of resin and magnetic beads we offer. 

Not sure which tag to use? See our affinity tag overview table HERE.

Additionally we offer activated resins and MagBeads for coupling to amino, thiol and carboxy groups directly.
 

Table 1: Different affinities for different applications
AffinitySpecificationProtein binding
His-tag-Affinity Agarose & MagBeads Due to its very small size it rarely affects protein function. High protein yields! His-tagged proteins
Glutathione / GST-tag Agarose & MagBeads The GST-tag is a 26 kDa protein tag which is often chosen to promote recombinant protein folding. GST-tagged proteins (Glutathione-S-Tranferase)
Strep-tag Affinity Agarose & MagBeads The Strep-tag® is a 8 amino acid tag with high specificity for StrepTactin®. Highly specific. Strep-tagged proteins
Rho1D4 / 1D4-tag Affinity Agarose & MagBeads The-Rho1D4-tag is a 9 amino acid tag that binds to the rho1D4 antibody. Our most specific affinity tag! Rho1d4-tagged proteins
Hydrophobic Interaction Agarose Agarose resin / MagBeads that carry a hydrophobic group for matching interactions with a protein. Hydrophobic amino acid residues.
Alprenolol Resins A resin for a highly spezialized purpose. ß-adrenergic receptors and alkene functions

Furthermore we offer more specialized IMAC resins and other affinities coupled to the NTA or IDA ligand.
 
Table 2: Special IMAC resins / MagBeads for more specialized purposes.
ProductsDescriptionAffinity
Cu-NTA Agarose / MagBeads Cu2+ coupled to NTA ligand Copper-binding and His-tagged proteins
Zn-NTA Agarose / MagBeads Zn2+ coupled to NTA ligand Zinc-binding (e.g Zinc-finger) proteins

Our Activated resins offer a wide selection of different active groups on the resin / MagBead. A possible application these products is the coupling of an antibody to them.
Table 3: Activated resins and MagBeads for specialized applications.
Active groupSpecificationCoupling to which group
Carboxy Agarose & MagBeads Resin carrys a free carboxyl group Amine
NHS activated Agarose & MagBeads Resin carrys a N-hydroxy-succinimide (NHS) functionality Amine
Amine activated Agarose & MagBeads Resin carrys a free amino group Carboxy
Epoxy activated Agarose & MagBeads Resin carrys a free epoxy group Amine or Thiol
Maleimide activated Agarose & MagBeads Resin carrys a free maleimide group Thiol
 
Top seller
PureCube 100 Ni-NTA Agarose PureCube 100 Ni-NTA Agarose
Article number: 74103
PureCube Ni-NTA Agarose PureCube Ni-NTA Agarose
Article number: 31103
PureCube Ni-NTA MagBeads PureCube Ni-NTA MagBeads
Article number: 31201
PureCube Fe-NTA MagBeads PureCube Fe-NTA MagBeads
Article number: 31501-Fe
PureCube Carboxy Agarose PureCube Carboxy Agarose
Article number: 50103
PureCube INDIGO Ni-MagBeads PureCube INDIGO Ni-MagBeads
Article number: 75201
Protein Purification Products
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PureCube Amine Activated Agarose PureCube Amine Activated Agarose
Cube Biotech offers Amine Activated Agarose resin to couple biomolecules via EDC (e.g. proteins) for affinity purification.
Article number: 51003
Sales price: From €120.00 *
PureCube Ni-NTA Agarose XL PureCube Ni-NTA Agarose XL
XL Sized Ni-NTA Agarose resin beads for His Tag protein purification. | ~Ø 400 µm bead diameter.| For viscous cell lystates.
Article number: 55103
Sales price: From €158.00 *
PureCube Alprenolol Agarose PureCube Alprenolol Agarose
100 % specialized for protein purification of ß-adrenergic receptor proteins. Alprenolol Agarose resin for batch spin & FPLC.
Article number: 56031
Sales price: From €808.00 *
PureCube 100 INDIGO Ni-Cartridge PureCube 100 INDIGO Ni-Cartridge
Our exclusive & high quality INDIGO-Ni agarose resin pre-filled in FPLC Cartridges / Columns for your His Tag purifications!
Article number: 75301
Sales price: From €57.00 *
PureCube Zn-NTA Agarose PureCube Zn-NTA Agarose
Cube Biotech offers Zinc-NTA agarose resin for His Tag purification and zinc finger protein enrichment.
Article number: 31403-Zn
Sales price: From €125.00 *
PureCube Rho1D4 MagBeads PureCube Rho1D4 MagBeads
PureCube magnetic beads with Rho1D4 / 1D4-tag affinity. For highly specific and ~100% pure membrane protein purifications.
Article number: 33201
Sales price: From €286.00 *
PureCube Compact Cartridge HiCap StrepTactin PureCube Compact Cartridge HiCap StrepTactin
FPLC Cartridge for Strep Tag based protein purification using Streptactin Agarose resin. Highest protein purity in reach!
Article number: 34302
Sales price: From €129.00 *
PureCube Fe-NTA Agarose PureCube Fe-NTA Agarose
PureCube High quality Fe-NTA agarose resin for the enrichment of phosphorylated peptides. | Automated assays possible
Article number: 31403-Fe
Sales price: From €125.00 *
PureCube Cu-NTA MagBeads PureCube Cu-NTA MagBeads
For Copper-Binding and for His-tagged protein. | Cu-NTA agarose for highest protein yield of his tagged proteins.
Article number: 31501-Cu
Sales price: From €80.00 *
PureCube Zn-NTA MagBeads PureCube Zn-NTA MagBeads
Enrichment of zinc finger proteins has never been easier! PureCube Zn-NTA magnetic beads for maximum purity & yield!
Article number: 31501-Zn
Sales price: From €80.00 *
HisCube - Ni-INDIGO His-Tag Protein Purification MINI Kit HisCube - Ni-INDIGO His-Tag Protein...
Fast & easy | Our HisCube MINI Kit for small scale His-tag protein purifications assays. | For maximum protein purity & yield
Article number: 80101
Sales price: €534.00 *
Cube MagBead Separator (1) Cube MagBead Separator (1)
Our Separator for magnetic beads comes with a practical ★modular★ design and strong magnets. No loss of magnetic bead again.
Article number: 16941
Sales price: From €74.00 *
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