Proteins
ACE2 (Angiotensin-converting enzyme 2) is a carboxypeptidase that is located on the cells surface. It is most commonly known for it role as the entry point of the coronavirus (COVID-19 pandemic). We offer this protein full-length and its exo-domain as individual products.
The protein is available off-the shelf, ready for ligand binding studies, crystallization, and other biochemical/biophysical experiments.

Features

Protein ACE2 (Angiotensin-converting enzyme 2)
Alternative names Angiotensin-converting enzyme homolog (ACEH); Angiotensin-converting enzyme-related carboxypeptidase (ACE-related carboxypeptidase);
UniProt number Q9BYF1
Protein classes Single span transmembrane protein, Carboxypeptidase
Organism Human (Homo sapiens)
Sequence

Ectodomain (AA 1 – 740), wildtype sequence and C-terminal 6 x His tag (red)


MSSSSWLLLS LVAVTAAQST IEEQAKTFLD KFNHEAEDLF YQSSLASWNY NTNITEENVQ NMNNAGDKWS AFLKEQSTLA QMYPLQEIQN LTVKLQLQAL QQNGSSVLSE DKSKRLNTIL NTMSTIYST GKVCNPDNPQ ECLLLEPGLN EIMANSLDYN ERLWAWESWR SEVGKQLRPL Y EEYVVLKN EMARANHYED YGDYWRGDYE VNGVDGYDYS RGQLIEDVEH TFEEIKPLYE HL HAYVRAK LMNAYPSYIS PIGCLPAHLL GDMWGRFWTNL YSLTVPFGQKP NIDVTDAMVD Q AWDAQRIF KEAEKFFVSV GLPNMTQGFWE NSMLTDPGNV QKAVCHPTAW DLGKGDFRIL M CTKVTMDD FLTAHHEMGH IQYDMAYAAQP FLLRNGANEG FHEAVGEIMS LSAATPKHLK S IGLLSPDF QEDNETEINF LLKQALTIVG TLPFTYMLE KWRWMVFKG EIPKDQWMKK WWEM KREIV GVVEPVPHD ETYCDPASLF HVSNDYSFIR YYTRTLYQFQ FQEALCQAA KHEGPLH KC DISNSTEAGQ KLFNMLRLGK SEPWTLALE NVVGAKNMNV RPLLNYFEPL FTWLKDQNK NSFVGWSTDW SPYADQSIKV RISLKSALGD KAYEWNDNEM YLFRSSVAYA MRQYFLKVKN QMILFGEED VRVANLKPRI SFNFFVTAPK NVSDIIPRTE VEKAIRMSRS RINDAFRLND NSLEFLGIQ PTLGPPNQPP VSHHHHHH

Affinity tags C-terminal His-tag
Size (excluding additional elements) 86,1 kDa
Expression system Hek293 mammalia cells
Purified via Ni-INDIGO Agarose and Size Exclusion Chromatograpy
Buffer 20 mM Hepes, 100 mM NaCl; pH 7.4
Purity (SDS-PAGE) >95 % as determined by SDS-PAGE
Homogeneity Size exclusion chromatography
Function Host cell receptor for virus entry, Protease
Top seller
ACE2 Ectodomain by Cube Biotech ACE2 receptor (Ectodomain)
Article number: 28621
ACE2
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ACE2 Ectodomain by Cube Biotech ACE2 receptor (Ectodomain)
ACE2 is the gateway of the coronavirus SARS-CoV-2 into our body. We offer this protein for your research!
Article number: 28621
Sales price: From €258.00 *
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