Activated Agaroses resins | Epoxy, NHS, maleimide & more | Cube Biotech

Activated Resins


Agarose Guide
Activated Agaroses are available as off-the-shelf items in quantities from 10 mL to several liters. They can be used to couple molecules of your choice in your laboratory. Our careful in-house production provides low lot-to-lot variation, making activated agaroses also suitable for commercial production.

PureCube Activated Agaroses provide:

  • Pre-activated matrices for coupling to proteins, peptides, or antibodies
  • Easy to follow protocols and expert technical support
  • Highly reproducible synthesis in our own laboratories
  • Off the shelf and tailor-made for your applications
  • Also available as Activated MagBeads
Download our Activated Resin Overview Table!
activated_protein_resins; protein_purification
Overview of our activated MagBeads and their respective chemistry coupling mechanisms
PureCube Activated AgaroseCoupling ChemistryCoupling mechanism
Carboxy-activated Agarose EDC/NHS Covalent, via amine groups
NHS-activated Agarose direct Fast and easy protocol Covalent, via amine groups Easy coupling of antibodies
Epoxy-activated Agarose direct Coupling of thermostable proteins and small molecules via amine and thiol
Amine-activated Agarose direct Covalent, via carboxy groups
Maleimide-activated Agarose direct Covalent, via cysteine groups

Activated Agarose resins from Cube Biotech were successfully used in the following publications and patents:

Targeted ProteinActivated chemical groupYearAuthor
cap-specific nucleoside 2′-O-methyltransferase. Maleimide 2016 Roos T., Yazdan Oanah B., Conzelmann M., Thess A., Buob D., Kunze M., Wagner V.2016-August-121
Recombinant mutant PPases Maleimide 2018 Kunze M., Hadler F.N., Yazdan Panah B.,Ross T. 2
P2-GM1os Maleimide 2019 Mahon C.S., Wildsmith G.C., Haksar D., de Poel E., Beekman J.M., Pieters R.J., Webb M.E., Turnbill W.B.3

References

1. Roos T., Yazdan Oanah B., Conzelmann M., Thess A., Buob D., Kunze M., Wagner V. inventor; Method for adding cap structures to rna using immobilized enzymes. International patent: WO2016193226A1. 2016-December-08
2. Kunze M., Hadler F.N., Yazdan Panah B.,Ross T. inventor; CureVae AG, Tübingen, Immobilized Inorganic Pyrophosphatase (Ppase), Us-Patent: US 2019 / 0177714 A1; September-21-2018
3. Mahon S. et al. (2019). A ‘catch-and-release’ receptor for the cholera toxin. Faraday Discussions. 10.1039/C9FD00017H.
Agarose Guide
Activated Agaroses are available as off-the-shelf items in quantities from 10 mL to several liters. They can be used to couple molecules of your choice in your laboratory. Our careful in-house production provides low lot-to-lot variation, making activated agaroses also suitable for commercial production.

PureCube Activated Agaroses provide:

  • Pre-activated matrices for coupling to proteins, peptides, or antibodies
  • Easy to follow protocols and expert technical support
  • Highly reproducible synthesis in our own laboratories
  • Off the shelf and tailor-made for your applications
  • Also available as Activated MagBeads
Download our Activated Resin Overview Table!
activated_protein_resins; protein_purification
Overview of our activated MagBeads and their respective chemistry coupling mechanisms
PureCube Activated AgaroseCoupling ChemistryCoupling mechanism
Carboxy-activated Agarose EDC/NHS Covalent, via amine groups
NHS-activated Agarose direct Fast and easy protocol Covalent, via amine groups Easy coupling of antibodies
Epoxy-activated Agarose direct Coupling of thermostable proteins and small molecules via amine and thiol
Amine-activated Agarose direct Covalent, via carboxy groups
Maleimide-activated Agarose direct Covalent, via cysteine groups

Activated Agarose resins from Cube Biotech were successfully used in the following publications and patents:

Targeted ProteinActivated chemical groupYearAuthor
cap-specific nucleoside 2′-O-methyltransferase. Maleimide 2016 Roos T., Yazdan Oanah B., Conzelmann M., Thess A., Buob D., Kunze M., Wagner V.2016-August-121
Recombinant mutant PPases Maleimide 2018 Kunze M., Hadler F.N., Yazdan Panah B.,Ross T. 2
P2-GM1os Maleimide 2019 Mahon C.S., Wildsmith G.C., Haksar D., de Poel E., Beekman J.M., Pieters R.J., Webb M.E., Turnbill W.B.3

References

1. Roos T., Yazdan Oanah B., Conzelmann M., Thess A., Buob D., Kunze M., Wagner V. inventor; Method for adding cap structures to rna using immobilized enzymes. International patent: WO2016193226A1. 2016-December-08
2. Kunze M., Hadler F.N., Yazdan Panah B.,Ross T. inventor; CureVae AG, Tübingen, Immobilized Inorganic Pyrophosphatase (Ppase), Us-Patent: US 2019 / 0177714 A1; September-21-2018
3. Mahon S. et al. (2019). A ‘catch-and-release’ receptor for the cholera toxin. Faraday Discussions. 10.1039/C9FD00017H.
Activated Resins
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PureCube Maleimide Activated Agarose PureCube Maleimide Activated Agarose
2 ml 50% Maleimide-Activated Agarose, for direct, irreversible coupling of biomolecules via thiol groups For more information read here:...
Article number: 51103
Sales price: From €295.00 *
PureCube NHS Activated Agarose PureCube NHS Activated Agarose
2 ml 50% NHS-Activated Agarose, for direct coupling of biomolecules via amine groups For more information read here: https://cube-biotech.com/products/purification-resins/activated-resins/nhs-activated-agarose/#
Article number: 50303
Sales price: From €112.00 *
PureCube Carboxy Agarose PureCube Carboxy Agarose
2 ml 50% Carboxy Agarose, for coupling of biomolecules via amine groups using EDC/NHS For more information read here: https://cube-biotech.com/products/purification-resins/activated-resins/carboxy-agarose/#
Article number: 50103
Sales price: From €85.00 *
PureCube Epoxy Activated Agarose PureCube Epoxy Activated Agarose
Lyophilized resin for 2 ml 50% Epoxy activated Agarose ► For coupling of biomolecules via amine or thiol groups.
Article number: 50703
Sales price: From €100.00 *
PureCube Amine Activated Agarose PureCube Amine Activated Agarose
2 ml 50% Amine-Activated Agarose, for coupling of biomolecules via carboxy groups using EDC/NHS For more information read here: https://cube-biotech.com/products/purification-resins/activated-resins/amine-activated-agarose/#
Article number: 51003
Sales price: From €100.00 *
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