Dodecylmaltoside (DDM)
Mild, non-ionic detergents such as dodecylmaltoside are well suited for the solubilization, stabilization, and purification of membrane proteins. For screening of the best-suited detergent for a given application, we offer maltosides with chain lengths from C-9 to C-13. Please
contact us if you are interested in purchasing bulk quantities of this detergent.
Ni-NTA Agarose from Cube Biotech was successfully used in the following publications:
| Protein | Year | Author |
|---|
| Solubilzed protein | 2019 | Worms D., Maertens B., Kubicek J., Subhramanyam U.K.T., Labahn J.1 |
| LHCII | 2019 | Akhtar P., Görföl F., Garab G., Lambrev P.H.2 |
| LHCII | 2019 | Tukus M., Akthar P., Chmmeliov., Görföl F., Trinkunas G., Lambrev P.H., Valkunas L.3 |
| OLPVRII | 2019 | Bratanov D., Kovalev K., Machtens J-P., Astashkin R., Chizov I., Soloviov D., Volkov D., Polovinkin V., Zabelskii D., Mager T., Gushchin I., Rokitsaya T., Antonenko Y., Alekseev A., Shevchenko V., Yutin N., Resselli R., Baeken C., Borshchevskiy V., Bourenkov G.P., Popov A.N., Balandin T., Büldt G. Manstein D.J., Rodriguez-Valera F., Fahlke C., Bamberg E., Koonin E., Gordeliy V.,4 |
Features
| | Dodecylmaltoside |
|---|
| Synonyms | n-Dodecyl β-maltoside, DDM, Lauryl-beta-D-maltoside, Lauryl-maltoside, LMT |
| Molecular weight | 510.63 g/mol |
| CAS-No. | 69227-93-6 |
| Purity | crystallization-grade, >99.5 % |
| Form | white crystalline powder |
| CMC (in H2O) | 0.17 mM (0.0087%) |
References
1. Worm D., et al. (2019) "Expression, purification and stabilization of human serotonin transporter from E. coli" Protein Expression and Purification Volume 164, December 2019, 105479 DOI: 10.1016/j.pep.2019.105479
2. Akhtar P. et al. (2019). Dependence of Chlorophyll Fluorescence Quenching on the Lipid-to-Protein Ratio in Reconstituted Light-Harvesting Complex II Membranes Containing Lipid Labels. Chemical Physics. 522. 10.1016/j.chemphys.2019.03.012.
3. Tutkus, M., (2018). Fluorescence Microscopy of Single Liposomes with Incorporated Pigment–Proteins. Langmuir. 34. 10.1021/acs.langmuir.8b02307.
4.Bratanov, D. et al. (2019). Unique structure and function of viral rhodopsins. Nature Communications. 10. 10.1038/s41467-019-12718-0.
