Need pure, active, wild-type membrane proteins - in nanodiscs?

Membrane proteins, in particular GPCRs, are the most pharmaceutically relevant protein class. At the same time, it is very difficult to obtain them in pure, active form. Cube Biotech's protein experts have worked hard to produce human GPCRs and other membrane proteins in sufficient quality that we can now offer to the community. GPCRs are both available solubilized in detergent, or reconstituted into nanodiscs for stabilization.

 

NEW: Colored membrane proteins are now available that can be used as controls in protein crystallization, and biochemical/biophysical assays.

 

Whether you are planning to perform biophysical or biochemical experiments with the currently offered target proteins, or simply use them as positive controls to set up your targets of interest, we will be happy to discuss the quantities you need.

 

 


Target Short

 

Target Name

  Origin      Form   

Product

page

MC4R   Melanocortin receptor   Human     Detergent  

GPBAR1/TGR5

 

 G-protein coupled bile receptor 1

  Human  
 

Detergent

 

GLP1R

 

Glucagon-like peptide receptor 1

  Human  
 

Detergent

 

OPRM1  

Mu-type opioid receptor

  Human  
 

Nanodisc

 
NTSR1  

Neurotensin receptor type 1

  Human  
 

Detergent

 
BR  

Bacteriorhodopsin

 

Halobacterium

salinarum

 
 

Detergent

 
HsSR-1  

Sensory rhodopsin-1

 

Halobacterium

salinarum

 
 

Detergent

 
HsSR-2   Sensory rhodopsin-2  

Halobacterium

salinarum

 
 

Detergent

 
NpSR-2  

Sensory rhodopsin-2

 

Natronomonas

pharaonis

 
 

Detergent

 
CaChR1   Channelrhodopsin 1  

Chloromonas

augustae

 
 

Detergent