ACE2 receptor (Ectodomain)

$349.20 *

Prices plus VAT plus shipping costs

Ready to ship today,
Delivery time appr. 1-3 workdays

µG:

  • 28621
ACE2 (Angiotensin-converting enzyme 2) is the gateway of the coronavirus SARS-CoV-2 into our... more
Product information "ACE2 receptor (Ectodomain)"
Product Type: ACE2
ACE2 (Angiotensin-converting enzyme 2) is the gateway of the coronavirus SARS-CoV-2 into our cell. Its actual cellular function is that of a cell surface-bound carboxypeptidase. We provide you with the Ectodomain of ACE2, ready for ligand binding studies, crystallization, and other biochemical/biophysical experiments.

PDF Downloads

 
SPIKE in MSP nanodisc, Gel filtrationSDS-PAGE and subsequent western blot showing the Ectodomain of ACE2. The His-tagged protein was purified using INDIGO-Ni agarose.
ELISA binding assay ACE2 ectodomainThe ACE2 ectodomain was immobilized at a concentration of 500 ng per well, the trimeric CoV-2 spike protein was used in triplicates at concentrations between 1 x 10-9M and 2 x 10-5M. The apparent KD value is approx. 2x 10-8M.

Features

 
Protein ACE2 (Angiotensin-converting enzyme 2)
Alternative names Angiotensin-converting enzyme homolog (ACEH); Angiotensin-converting enzyme-related carboxypeptidase (ACE-related carboxypeptidase);
UniProt number Q9BYF1
Protein classes Single span transmembrane protein, Carboxypeptidase
Organism Human (Homo sapiens)
Sequence

Ectodomain (AA 1 – 740), wildtype sequence and C-terminal 6 x His tag (red)


MSSSSWLLLS LVAVTAAQST IEEQAKTFLD KFNHEAEDLF YQSSLASWNY NTNITEENVQ NMNNAGDKWS AFLKEQSTLA QMYPLQEIQN LTVKLQLQAL QQNGSSVLSE DKSKRLNTIL NTMSTIYST GKVCNPDNPQ ECLLLEPGLN EIMANSLDYN ERLWAWESWR SEVGKQLRPL Y EEYVVLKN EMARANHYED YGDYWRGDYE VNGVDGYDYS RGQLIEDVEH TFEEIKPLYE HL HAYVRAK LMNAYPSYIS PIGCLPAHLL GDMWGRFWTNL YSLTVPFGQKP NIDVTDAMVD Q AWDAQRIF KEAEKFFVSV GLPNMTQGFWE NSMLTDPGNV QKAVCHPTAW DLGKGDFRIL M CTKVTMDD FLTAHHEMGH IQYDMAYAAQP FLLRNGANEG FHEAVGEIMS LSAATPKHLK S IGLLSPDF QEDNETEINF LLKQALTIVG TLPFTYMLE KWRWMVFKG EIPKDQWMKK WWEM KREIV GVVEPVPHD ETYCDPASLF HVSNDYSFIR YYTRTLYQFQ FQEALCQAA KHEGPLH KC DISNSTEAGQ KLFNMLRLGK SEPWTLALE NVVGAKNMNV RPLLNYFEPL FTWLKDQNK NSFVGWSTDW SPYADQSIKV RISLKSALGD KAYEWNDNEM YLFRSSVAYA MRQYFLKVKN QMILFGEED VRVANLKPRI SFNFFVTAPK NVSDIIPRTE VEKAIRMSRS RINDAFRLND N SLEFLGIQ PTLGPPNQPP VSHHHHHH

Affinity tags C-terminal His-tag
Size (excluding additional elements) 86,1 kDa
Expression system Hek293 mammalia cells
Purified via Ni-INDIGO Agarose and Size Exclusion Chromatograpy
Buffer 20 mM Hepes, 100 mM NaCl; pH 7.4
Purity (SDS-PAGE) >95 % as determined by SDS-PAGE
Homogeneity Size exclusion chromatography
Function Host cell receptor for virus entry, Protease
Related links to "ACE2 receptor (Ectodomain)"
tube containing SPIKE mutant protein SARS CoV-2 full-length Spike B.1.351 Mutation
Article number: 28719
Sales price: From $309.60 *
SPIKE in LMNG Mycelle, product image SARS CoV-2 spike protein in LMNG detergent
Article number: 28702
Sales price: From $904.80 *
Vial of 25 µg of Omicron Spike protein SARS CoV-2 full-length Spike B.1.1.529 /...
Article number: 28750
Sales price: From $309.60 *
Spike Protein Delta Variant SARS CoV-2 full-length Spike B.1.617.2 (Delta)...
Article number: 28744
Sales price: From $309.60 *
COVID-19 antibody RBD (spike protein) 100 µg COVID-19 antibody RBD (spike protein) 100 µg
Article number: 28802
Sales price: $391.20 *
GLP1R protein GLP1R protein
Article number: 28201
Sales price: From $1,446.00 *
Overview of all Synthetic polymers that are contained in the MAXI screening Kit Synthetic Nanodisc Screening Kit MAXI (16x2x50 mg)
Article number: 18295
Sales price: $702.00 * $780.00 *
SPIKE protein B.1.429 (CAl. 20C) SARS CoV-2 full-length Spike B.1.525 Mutation
Article number: 28733
Sales price: From $309.60 *
B.1.429 Corona mutant available at Cube Biotech SARS CoV-2 full-length Spike B.1.429 Mutation
Article number: 28736
Sales price: From $309.60 *
Tube SARS CoV-2 full-length Spike B.1.1.7 Mutation
Article number: 28716
Sales price: From $309.60 *
COVID-19 antibody S2α (spike protein) 100 µg COVID-19 antibody S2α (spike protein) 100 µg
Article number: 28803
Sales price: $391.20 *
COVID-19 Antibody S1 domain (spike protein) 100 µg COVID-19 Antibody S1 domain (spike protein) 100 µg
Article number: 28801
Sales price: $391.20 *
SARS-CoV-2 spike protein in SMALP 200 (25µg) SARS-CoV-2 spike protein in SMALP 200 (25µg)
Article number: 28715
Sales price: $1,183.20 *
SPIKE in MSP nanodisc, product image SARS CoV-2 Spike protein nanodisc complex
Article number: 29301
Sales price: From $1,377.60 *
AChR T. Californica AChR T. Californica
Article number: 28601
Sales price: From $758.40 *
MC4R protein MC4R protein
Article number: 28401
Sales price: From $1,302.00 *
Tube containing Ultrasolute™ Amphipol 18 Ultrasolute™ Amphipol 18 HEPES
Article number: 18321
Sales price: From $250.80 *
AASTY 11-50 AASTY 11-50
Article number: 18265
Sales price: From $250.80 *
SARS CoV-2 full-length Spike B.1.621 (Mu) Mutation SARS CoV-2 full-length Spike B.1.621 (Mu) Mutation
Article number: 28747
Sales price: From $309.60 *
RB-Domain of the SARS-CoV 2 mutant strain P.1 SARS CoV-2 Spike P.1 Mutation RBD domain
Article number: 28731
Sales price: From $662.40 *
SARS-CoV-2 P.1 spike protein SARS CoV-2 full-length Spike P.1 Mutation
Article number: 28722
Sales price: From $309.60 *
COVID-19 antibody S2β (spike protein) 100 µg COVID-19 antibody S2β (spike protein) 100 µg
Article number: 28804
Sales price: $391.20 *
SMALP 200 SMALP 200
Article number: 18210
Sales price: From $250.80 *
SMALP 300 SMALP 300
Article number: 18200
Sales price: From $250.80 *
Tube Containing DIBMA Glycerol TRIS DIBMA Glycerol, TRIS
Article number: 18054
Sales price: From $234.00 * $274.80 *
Tube containing DIBMA Glucosamine TRIS DIBMA Glucosamine, TRIS
Article number: 18044
Sales price: From $234.00 * $274.80 *
PureCube Compact Cartridge Al-NTA PureCube Compact Cartridge Al-NTA
Article number: 31602-Al
Sales price: From $52.80 *
PureCube Cu-NTA MagBeads PureCube Cu-NTA MagBeads
Article number: 31501-Cu
Sales price: From $96.00 *
PureCube Al-NTA Agarose PureCube Al-NTA Agarose
Article number: 31403-Al
Sales price: From $150.00 *
PureCube Zn-NTA Agarose PureCube Zn-NTA Agarose
Article number: 31403-Zn
Sales price: From $150.00 *
PureCube 100 INDIGO Ni-Agarose PureCube 100 INDIGO Ni-Agarose
Article number: 75103
Sales price: From $121.20 * $151.20 *
10X Tris-EDTA (TE), pH 7.4 (10 L) 10X Tris-EDTA (TE), pH 7.4 (10 L)
Article number: 61278
Sales price: $290.40 *
PureCube Maleimide Activated Agarose XL PureCube Maleimide Activated Agarose XL
Article number: 59103
Sales price: From $549.60 *
PureCube Carboxy MagBeads XL PureCube Carboxy MagBeads XL
Article number: 58201
Sales price: From $153.60 *
PureCube Rho1D4 MagBeads XL PureCube Rho1D4 MagBeads XL
Article number: 57701
Sales price: From $423.60 *
PureCube NHS Activated Agarose PureCube NHS Activated Agarose
Article number: 50303
Sales price: From $278.40 *
PureCube Carboxy MagBeads PureCube Carboxy MagBeads
Article number: 50201
Sales price: From $118.80 *
PureCube Butyl Agarose PureCube Butyl Agarose
Article number: 39003
Sales price: From $78.00 *
Rho Starter Set 1: PureCube Rho1D4 Agarose (1 ml) + Rho1D4 peptide (5 mg) Rho Starter Set 1: PureCube Rho1D4 Agarose (1...
Article number: 33199
Sales price: $236.40 * $472.80 *
PureCube Glutathione Agarose PureCube Glutathione Agarose
Article number: 32103
Sales price: From $157.20 * $196.80 *
Viewed