SARS CoV-2 full-length Spike B.1.1.7 Mutation

$274.80 *

Prices plus VAT plus shipping costs

Ready to ship today,
Delivery time appr. 1-3 workdays

µG:

  • 28716
All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune... more
Product information "SARS CoV-2 full-length Spike B.1.1.7 Mutation"
Product Type: Mutant Spike Protein
Protein Sequence: Full-length
All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose. To help the sciencific community to combat these mutants Cube Biotech offers the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent.

This is the spike protein of the mutant strain B.1.1.7, also commonly known as the "UK / Great Britain mutant". Its individual mutations are listed in the "features" table below.
Further SPIKE related products by Cube Biotech include:
    1. SPIKE of mutant strain B.1.351, also known as the "South Africa mutant" in LMNG.
    2. SPIKE of mutant strain B.1.351/CAL.20, also known as the "California mutant" in LMNG.
    3. SPIKE of mutant strain B.1.525 in LMNG.
    4. SPIKE of mutant strain P.1, also known as the "Brazil Mutant" in LMNG.
    5. The "original" SPIKE protein in LMNG.
    6. The ectodomain of ACE2 - SPIKE's contact on the cell surface
    7. Anti-SPIKE antibodies

PDF Downloads

Uk mutant SPIKE in SDS page, westernblotFigure 1: Data from our lab regarding SPIKE stabilized in a detergent mycelle.
A: SDS-Page of purified SPIKE in detergent mycelle.
B: Western blot of Rho1d4 tagged SPIKE, originated from the SDS Page seen in "A".

Features

Alternative names SPIKE_SARS2 Spike glycoprotein
UniProt number P0DTC2
Protein class Single span transmembrane protein
Organism Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
Mutation that differ from "original" SPIKE protein del 69-70
del 144
N501Y
A570D
D614G
P681H
T716I
Further modifications
  • furin cleavage site “RRAR” mutated to “GSAG”; KV986PP
  • C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence
Affinity tag C-terminal Rho1D4
Expression Host Hek293 Expi cells
Size 1286 amino acids (including Rho1D4 tag and linker)
142114 Da
Buffer composition 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001 % LMNG
Function host cell surface receptor binding; fusion of virus membrane with host endosome membrane
Purity (SDS-PAGE) >98% as determined by SDS-PAGE, see Fig. 1 A and B
Related links to "SARS CoV-2 full-length Spike B.1.1.7 Mutation"
tube containing SPIKE mutant protein SARS CoV-2 full-length Spike B.1.351 Mutation
Article number: 28719
Sales price: From $274.80 *
SPIKE in LMNG Mycelle, product image SARS CoV-2 spike protein in LMNG detergent
Article number: 28702
Sales price: From $804.00 *
SARS-CoV-2 P.1 spike protein SARS CoV-2 full-length Spike P.1 Mutation
Article number: 28722
Sales price: From $274.80 *
Rho1D4 antibody (0.2 mg) Rho1D4 antibody (0.2 mg)
Article number: 40020
Sales price: $345.60 *
tube containing SPIKE mutant protein SARS CoV-2 full-length Spike B.1.351 Mutation
Article number: 28719
Sales price: From $274.80 *
SPIKE in LMNG Mycelle, product image SARS CoV-2 spike protein in LMNG detergent
Article number: 28702
Sales price: From $804.00 *
RBD Domain of SPIKE from Mutant strain B.1.1.7 SARS CoV-2 Spike B.1.1.7 Mutation RBD domain
Article number: 28727
Sales price: From $588.00 *
SARS-CoV-2 P.1 spike protein SARS CoV-2 full-length Spike P.1 Mutation
Article number: 28722
Sales price: From $274.80 *
SARS CoV-2 spike protein set in LMNG detergent (100 µg), DIBMA Glycerol (25 µg) and nanodisc complex SARS CoV-2 spike protein set in LMNG detergent...
Article number: 28704
Sales price: $2,830.80 *
Product Image SPIKE protein in DIBMA SARS CoV-2 spike protein in DIBMA Glycerol
Article number: 28706
Sales price: From $1,051.20 *
SPIKE in MSP nanodisc, product image SARS CoV-2 Spike protein nanodisc complex
Article number: 29301
Sales price: From $1,224.00 *
SARS CoV-2 full-length Spike B.1.621 (Mu) Mutation SARS CoV-2 full-length Spike B.1.621 (Mu) Mutation
Article number: 28747
Sales price: From $274.80 *
SARS-CoV-2 spike protein in SMALP 140 (25 µg) SARS-CoV-2 spike protein in SMALP 140 (25 µg)
Article number: 28711
Sales price: $1,366.80 *
ACE2 Ectodomain by Cube Biotech ACE2 receptor (Ectodomain)
Article number: 28621
Sales price: From $309.60 *
Spike Protein Assay Set (4x100µg antibody + 100µg CoV-2 spike protein in LMNG) Spike Protein Assay Set (4x100µg antibody +...
Article number: 28811
Sales price: $1,755.60 *
COVID-19 antibody S2β (spike protein) 100 µg COVID-19 antibody S2β (spike protein) 100 µg
Article number: 28804
Sales price: $346.80 *
COVID-19 antibody RBD (spike protein) 100 µg COVID-19 antibody RBD (spike protein) 100 µg
Article number: 28802
Sales price: $346.80 *
Spike Protein Delta Variant SARS CoV-2 full-length Spike B.1.617.2 (Delta)...
Article number: 28744
Sales price: From $274.80 *
SARS CoV-2 Spike B.1.351 Mutation RBD domain SARS CoV-2 Spike B.1.351 Mutation RBD domain
Article number: 28729
Sales price: From $588.00 *
SARS-CoV-2 spike protein in SMALP 200 (25µg) SARS-CoV-2 spike protein in SMALP 200 (25µg)
Article number: 28715
Sales price: $1,051.20 *
SMALP 300 SMALP 300
Article number: 18200
Sales price: From $222.00 *
PureCube Glutathione Agarose PureCube Glutathione Agarose
Article number: 32103
Sales price: From $139.20 * $174.00 *
OPRM1 protein nanodisc complex OPRM1 protein nanodisc complex
Article number: 29001
Sales price: From $1,959.60 *
Ca Channelopsin 1 Ca Channelopsin 1
Article number: 28941
Sales price: $757.20 *
MC4R protein MC4R protein
Article number: 28401
Sales price: From $1,156.80 *
NTSR1 protein NTSR1 protein
Article number: 28301
Sales price: From $1,156.80 *
GPBAR1 (TGR5) protein GPBAR1 (TGR5) protein
Article number: 28101
Sales price: From $1,285.20 *
SPIKE protein B.1.429 (CAl. 20C) SARS CoV-2 full-length Spike B.1.525 Mutation
Article number: 28733
Sales price: From $274.80 *
B.1.429 Corona mutant available at Cube Biotech SARS CoV-2 full-length Spike B.1.429 Mutation
Article number: 28736
Sales price: From $274.80 *
COVID-19 antibody S2α (spike protein) 100 µg COVID-19 antibody S2α (spike protein) 100 µg
Article number: 28803
Sales price: $346.80 *
SMALP 200 SMALP 200
Article number: 18210
Sales price: From $222.00 *
PureCube 100 INDIGO Ni-Agarose PureCube 100 INDIGO Ni-Agarose
Article number: 75103
Sales price: From $107.52 * $134.40 *
PureCube Epoxy Activated MagBeads XL PureCube Epoxy Activated MagBeads XL
Article number: 58805
Sales price: From $666.00 *
PureCube Phenyl Agarose PureCube Phenyl Agarose
Article number: 39103
Sales price: From $68.40 *
PureCube Co-NTA Agarose PureCube Co-NTA Agarose
Article number: 31403
Sales price: From $106.56 * $133.20 *
PureCube Ni-NTA Agarose PureCube Ni-NTA Agarose
Article number: 31103
Sales price: From $98.88 * $123.60 *
GLP1R protein GLP1R protein
Article number: 28201
Sales price: From $1,285.20 *
Nanodisc MSP1D1 dH5-His DMPG (50 µL) Nanodisc MSP1D1 dH5-His DMPG (50 µL)
Article number: 26325
Sales price: $457.92 * $508.80 *
MSP2N2, lyophilized protein MSP2N2, lyophilized protein
Article number: 26182
Sales price: From $374.40 *
MSP1E3D1-His, lyophilized protein MSP1E3D1-His, lyophilized protein
Article number: 26152
Sales price: From $141.48 * $157.20 *
Rho1D4 peptide Rho1D4 peptide
Article number: 16201
Sales price: From $133.20 *
n-Decyl-phosphocholine (Fos-choline-10) n-Decyl-phosphocholine (Fos-choline-10)
Article number: 16041
Sales price: From $147.60 *
n-Tridecyl-phosphocholine (Fos-choline-13) n-Tridecyl-phosphocholine (Fos-choline-13)
Article number: 16025
Sales price: From $169.20 *
n-Octyl-1-thio-beta-D-glucopyranoside (OTG) n-Octyl-1-thio-beta-D-glucopyranoside (OTG)
Article number: 16018
Sales price: From $178.80 *
Viewed