SARS CoV-2 Spike B.1.351 Mutation RBD domain
- Order number: 28729
All viruses undergo fast mutations and adept quickly to the countermeasures that the immune... more
Product information "SARS CoV-2 Spike B.1.351 Mutation RBD domain"
| Product Type: | Mutant Spike Protein |
| Protein Sequence: | RB Domain |
All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. To help the science combat these mutants Cube Biotech offers the RB-Domains of these mutant SPIKE proteins.
That is the full Receptor-Binding Domain of the SPIKE surface protein SARS-CoV-2 of the mutant strain B.1.351, also commonly known as the "SA / South Africa mutant". Its individual mutations are listed in the "features" table below.
Further SPIKE related products by Cube Biotech include:
Figure 1: Size, purity and oligomerization state of CoV-2 spike protein RBD domain assessed by SDS-PAGE, Western Blot using an anti-His antibody.
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Figure 1: Size, purity and oligomerization state of CoV-2 spike protein RBD domain assessed by SDS-PAGE, Western Blot using an anti-His antibody.Features
| Alternative names | SPIKE_SARS2 Spike glycoprotein |
| UniProt number | P0DTC2 |
| Protein class | Single span transmembrane protein |
| Organism | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2) |
| Sequence | RBD domain (aa 319 – 537), K417N, E484K, N501Y, C-terminal His-tag |
| Affinity tag | C-terminal His-tag |
| Expression Host | Hek293 Expi cells |
| Size | 225 amino acids (including His-tag) 25491 Da |
| Buffer composition | 20 mM Hepes pH 7.5; 150 mM NaCl |
| Function | host cell surface receptor binding; fusion of virus membrane with host endosome membrane |
| Purity (SDS-PAGE) | >98% as determined by SDS-PAGE, see Fig. 1 A and B |
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Article number: 28747
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