
- Order number: 28729
All viruses undergo fast mutations and adept quickly to the countermeasures that the immune... more
Product information "SARS CoV-2 Spike B.1.351 Mutation RBD domain"
Product Type: | Mutant Spike Protein |
Protein Sequence: | RB Domain |
All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. To help the science combat these mutants Cube Biotech offers the RB-Domains of these mutant SPIKE proteins.
That is the full Receptor-Binding Domain of the SPIKE surface protein SARS-CoV-2 of the mutant strain B.1.351, also commonly known as the "SA / South Africa mutant". Its individual mutations are listed in the "features" table below.
Further SPIKE related products by Cube Biotech include:
Figure 1: Size, purity and oligomerization state of CoV-2 spike protein RBD domain assessed by SDS-PAGE, Western Blot using an anti-His antibody.
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Features
Alternative names | SPIKE_SARS2 Spike glycoprotein |
UniProt number | P0DTC2 |
Protein class | Single span transmembrane protein |
Organism | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2) |
Sequence | RBD domain (aa 319 – 537), K417N, E484K, N501Y, C-terminal His-tag |
Affinity tag | C-terminal His-tag |
Expression Host | Hek293 Expi cells |
Size | 225 amino acids (including His-tag) 25491 Da |
Buffer composition | 20 mM Hepes pH 7.5; 150 mM NaCl |
Function | host cell surface receptor binding; fusion of virus membrane with host endosome membrane |
Purity (SDS-PAGE) | >98% as determined by SDS-PAGE, see Fig. 1 A and B |
Related links to "SARS CoV-2 Spike B.1.351 Mutation RBD domain"

Article number: 28747
Sales price: From $309.60 *
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