Cube Nanodisc products


Nanodiscs provide an exciting alternative for the stabilization of membrane proteins. Cube Biotech offers everything you need to get started with this novel technology. There are two options to reconstitute membrane proteins into nanodiscs:

For the reconstitution of membrane proteins that are already isolated and solubilized in detergent, we recommend to use membrane scaffold proteins (MSPs) in combination with phospholipids. A variety of membrane scaffold proteins (MSPs) are available that can be assembled to nanodiscs of different sizes to accommodate proteins with varying numbers of transmembrane domains. His-tagged MSPs allow for easy detection of the nanodisc and even immobilization on SPR chips. On the other hand, if the protein of interest itself carries a his-tag, we recommend to use untagged MSP proteins. For use in cell-free expression reactions, empty nanodiscs are recommended. They can be assembled using our Nanodisc assembly kits, or purchased ready to use. Note that these kits only provide small amounts of nanodisc that are suitable for cell-free expression, and not recommended for direct reconstitution of already purified proteins.
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Cube Nanodisc products

Nanodiscs provide an exciting alternative for the stabilization of membrane proteins. Cube Biotech offers everything you need to get started with this novel technology. There are two options to reconstitute membrane proteins into nanodiscs:

For the reconstitution of membrane proteins that are already isolated and solubilized in detergent, we recommend to use membrane scaffold proteins (MSPs) in combination with phospholipids. A variety of membrane scaffold proteins (MSPs) are available that can be assembled to nanodiscs of different sizes to accommodate proteins with varying numbers of transmembrane domains. His-tagged MSPs allow for easy detection of the nanodisc and even immobilization on SPR chips. On the other hand, if the protein of interest itself carries a his-tag, we recommend to use untagged MSP proteins. For use in cell-free expression reactions, empty nanodiscs are recommended. They can be assembled using our Nanodisc assembly kits, or purchased ready to use. Note that these kits only provide small amounts of nanodisc that are suitable for cell-free expression, and not recommended for direct reconstitution of already purified proteins.
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Nanodisc Assembly Kit MSP1D1 dH5-His_POPC Nanodisc Assembly Kit MSP1D1 dH5-His_POPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1 delta H5 mutant, N-terminal 6xHis-tagged, 3.12 mg...
Article number: 26223
Sales price: €240.00 *
Nanodisc Assembly Kit MSP1D1_DMPC Nanodisc Assembly Kit MSP1D1_DMPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1, untagged, 4.65 mg...
Article number: 26231
Sales price: €458.00 *
Nanodisc Assembly Kit MSP1D1_POPC Nanodisc Assembly Kit MSP1D1_POPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1, untagged, 3.58 mg...
Article number: 26233
Sales price: €458.00 *
Nanodisc Assembly Kit MSP1D1 dH5_DMPC Nanodisc Assembly Kit MSP1D1 dH5_DMPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1 delta H5 mutant, untagged, 4.87 mg...
Article number: 26241
Sales price: €458.00 *
Nanodisc Assembly Kit MSP1D1 dH5_POPC Nanodisc Assembly Kit MSP1D1 dH5_POPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1 delta H5 mutant, untagged, 3.12 mg...
Article number: 26243
Sales price: €458.00 *
Nanodisc Assembly Kit MSP1E3D1-His_DMPC Nanodisc Assembly Kit MSP1E3D1-His_DMPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1E3, N-terminal 6xHis-tagged, 5.09 mg...
Article number: 26251
Sales price: €240.00 *
Nanodisc Assembly Kit MSP1E3D1-His_POPC Nanodisc Assembly Kit MSP1E3D1-His_POPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1E3, N-terminal 6xHis-tagged, 4.22 mg...
Article number: 26253
Sales price: €240.00 *
Nanodisc Assembly Kit MSP2N2-His _DMPC Nanodisc Assembly Kit MSP2N2-His _DMPC
Article number: 26271
Sales price: €300.00 *
Nanodisc Assembly Kit MSP2N2-His _POPC Nanodisc Assembly Kit MSP2N2-His _POPC
Article number: 26273
Sales price: €300.00 *
Nanodisc MSP1D1-His_DMPC (50 µL) Nanodisc MSP1D1-His_DMPC (50 µL)
50 microliter pre-assembled nanodisc, 0.5 mM concentrated, containing MSP1D1-His protein and DMPC. For use in cell-free reactions only. Product is shipped on dry ice - additional freight charges apply.  
Article number: 26311
Sales price: €402.00 *
Nanodisc MSP1D1-His_POPC (50 µL) Nanodisc MSP1D1-His_POPC (50 µL)
50 microliter pre-assembled nanodisc, 0.5 mM concentrated, containing MSP1D1-His protein and POPC. For use in cell-free reactions only. Product is shipped on dry ice - additional freight charges apply.    
Article number: 26313
Sales price: €402.00 *
Nanodisc MSP1D1-His_DMPG (50 µL) Nanodisc MSP1D1-His_DMPG (50 µL)
50 microliter pre-assembled nanodisc, 0.5 mM concentrated, containing MSP1D1-His protein and DMPG. For use in cell-free reactions only. Product is shipped on dry ice - additional freight charges apply.
Article number: 26315
Sales price: €402.00 *
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