Pure & Active Membrane Proteins


Proteins active

Need pure, active, wild-type membrane proteins - in nanodiscs?

Membrane proteins, in particular GPCRs, are the most pharmaceutically relevant protein class. At the same time, it is very difficult to obtain them in pure, active form. Cube Biotech's protein experts have worked hard to produce human GPCRs and other membrane proteins in sufficient quality that we can now offer to the community. GPCRs are both available solubilized in detergent, or reconstituted into nanodiscs for stabilization.

colored membrane proteins
Colored membrane proteins are available that can be used as controls in protein crystallization, and biochemical/biophysical assays.
Whether you are planning to perform biophysical or biochemical experiments with the currently offered target proteins, or simply use them as positive controls to set up your targets of interest, we will be happy to discuss the quantities you need.

Pure & Active membrane proteins from Cube Biotech were successfully used in the following publications:

YearAuthorProduct
2022 Ritzmann N.1 Hs Bacteriorhodopsin



ProteinTarget NameOriginForm of solubilization / stabilization
GPBAR1/TGR5 G-protein coupled bile receptor 1 Human Detergent
GLP1R Glucagon-like peptide receptor 1 Human Detergent
NTSR1 Neurotensin receptor type 1 Human Detergent
VGT Vesicular glutamate transporter 2 Human  
BR Bacteriorhodopsin Halobacterium salinarum Detergent
HsSR-1 Sensory rhodopsin-1 Halobacterium salinarum Detergent
HsSR-2 Sensory rhodopsin-2 Halobacterium salinarum Detergent
NpSR-2 Sensory rhodopsin-2 Natronomonas pharaonis Detergent
CaChR1 Channelrhodopsin 1 Chloromonas augustae Detergent
MC4R Melanocortin receptor 4 Homo sapiens Detergent
AChR Acetylcholin receptor 1 Torpedo Californica  
 
Pure & Active Membrane Proteins
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ACE2 Ectodomain by Cube Biotech ACE2 receptor (Ectodomain)
ACE2 is the gateway of the coronavirus SARS-CoV-2 into our body. We offer this protein for your research!
Article number: 28621
Sales price: From €291.00 *
tube containing SPIKE mutant protein SARS CoV-2 full-length Spike B.1.351 Mutation
Full-Length & active spike protein of the SARS-COV-2 mutant strain B.1.351, also known as the "South Africa" mutant.
Article number: 28719
Sales price: From €258.00 *
Tube SARS CoV-2 full-length Spike B.1.1.7 Mutation
Full-Length & active spike protein of the SARS-COV-2 mutant strain B.1.351, also known as the "UK" mutant.
Article number: 28716
Sales price: From €258.00 *
SARS-CoV-2 P.1 spike protein SARS CoV-2 full-length Spike P.1 Mutation
Full-Length & active spike protein of the SARS-COV-2 mutant strain B.1.351, also known as the "Brazil" mutant.
Article number: 28722
Sales price: From €258.00 *
RBD Domain of SPIKE from Mutant strain B.1.1.7 SARS CoV-2 Spike B.1.1.7 Mutation RBD domain
The Receptor Binding Domain (RBD) of the mutant SPIKE protein of SARS-CoV-2 strain B.1.1.7.
Article number: 28727
Sales price: From €552.00 *
SARS CoV-2 Spike B.1.351 Mutation RBD domain SARS CoV-2 Spike B.1.351 Mutation RBD domain
The Receptor Binding Domain (RBD) of the mutant SPIKE protein of SARS-CoV-2 strain B.1.351.
Article number: 28729
Sales price: From €552.00 *
RB-Domain of the SARS-CoV 2 mutant strain P.1 SARS CoV-2 Spike P.1 Mutation RBD domain
The Receptor Binding Domain (RBD) of the mutant SPIKE protein of SARS-CoV-2 strain P.1
Article number: 28731
Sales price: From €552.00 *
B.1.429 Corona mutant available at Cube Biotech SARS CoV-2 full-length Spike B.1.429 Mutation
Full-Length & active spike protein of the SARS-COV-2 mutant strain B.1.429, also known as the "California" mutant.
Article number: 28736
Sales price: From €258.00 *
SPIKE protein B.1.429 (CAl. 20C) SARS CoV-2 full-length Spike B.1.525 Mutation
Full-Length & active spike protein of the SARS-COV-2 mutant strain B.1.525.
Article number: 28733
Sales price: From €258.00 *
SARS CoV-2 full-length Spike B.1.621 (Mu) Mutation SARS CoV-2 full-length Spike B.1.621 (Mu) Mutation
Full-Length & active spike protein of the SARS-COV-2 mutant strain B.1.621, also known as the "Mu" mutant.
Article number: 28747
Sales price: From €258.00 *
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