Nanodisc MSP proteins


Membrane scaffold proteins (MSPs) are typically used for the reconstitution of already isolated proteins. A variety of MSPs are available that can be assembled to nanodiscs of different sizes to accommodate proteins with varying numbers of transmembrane domains. His-tagged MSPs allow for easy detection of the nanodisc and even immobilization on SPR chips. On the other hand, if the protein of interest itself carries a His-tag, we recommend to use untagged MSP proteins. For use in cell-free expression reactions, assembled nanodiscs are available.

Why Membrane scaffold proteins?

  • Variety of lyophilized membrane scaffold proteins available
  • Stable, lyophilized protein preparations in convenient aliquots
  • Can be combined with different phospholipids
  • Also available untagged and as mouse/rat homolog proteins

Different MSP nanodisc features in detail

There are several different components that a nanodisc is made from. Each with its own distinct role for the functionality of the MSP nanodisc. The following figure gives an overview of every possible composition and modification of MSP nanodiscs that we offer. In addition to the features listed down below, we also offer DIBMA and SMA based synthetic Nanodiscs.
Nanodisc differences Titleslide
 
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Nanodisc MSP proteins
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MSP1D1, lyophilized protein MSP1D1, lyophilized protein
Membrane scaffold protein (MSP)1D1, His-tag removed by proteolytic digest. 2 mg lyophilized protein
Article number: 26132
Sales price: From €283.00 *
MSP2N2-His, lyophilized protein MSP2N2-His, lyophilized protein
Membrane scaffold protein 2 N2, N-terminal 6xHis-tagged, 2 mg lyophilized protein
Article number: 26172
Sales price: From €185.00 *
MSP1E3D1-His, lyophilized protein MSP1E3D1-His, lyophilized protein
Membrane scaffold protein 1 E3D1, N-terminal 6xHis-tagged, 2 mg lyophilized protein
Article number: 26152
Sales price: From €148.00 *
MSP1D1 dH5-His, lyophilized protein MSP1D1 dH5-His, lyophilized protein
Membrane scaffold protein 1 D1 delta H5 mutant, N-terminal 6xHis-tagged, 2 mg lyophilized protein
Article number: 26122
Sales price: From €148.00 *
MSP2N2, lyophilized protein MSP2N2, lyophilized protein
Membrane scaffold protein (MSP) 2N2, His-tag removed by proteolytic digest. 2 mg lyophilized protein
Article number: 26182
Sales price: From €351.00 *
mouse MSP1D1, lyophilized protein mouse MSP1D1, lyophilized protein
(Mouse) Membrane scaffolding protein MSP1D1 for nanodisc assembly. For scaffolding diameters of 9-10 nanometers. Lyophilized.
Article number: 26532
Sales price: From €308.00 *
MSP1D1-D73C-His, lyophilized protein MSP1D1-D73C-His, lyophilized protein
The new MSP1D1-D73C-His nanodisc from Cube Biotech contains the amino acid cystein.
Article number: 27212
Sales price: From €185.00 *
MSP1D1-His, lyophilized protein MSP1D1-His, lyophilized protein
2 mg lyophilized membrane scaffold 1D1 protein, His-tagged.
Article number: 26112
Sales price: From €148.00 *
MSP1D1 dH5, lyophilized protein MSP1D1 dH5, lyophilized protein
Membrane scaffold protein MSP1D1ΔH5 with N-terminal His-tag, 2 mg lyophilized protein ► for nanodisc diameters of 7-8 nm
Article number: 26142
Sales price: From €283.00 *
MSP1E3D1, lyophilized protein MSP1E3D1, lyophilized protein
Membrane scaffold protein 1 E3D1, His-tag removed by protease digest. 2 mg lyophilized protein
Article number: 26162
Sales price: From €283.00 *
mouse MSP1D1-His, lyophilized protein mouse MSP1D1-His, lyophilized protein
Mouse membrane scaffold protein 1 D1, N-terminal 6xHis-tagged, 2 mg lyophilized protein
Article number: 26512
Sales price: From €170.00 *
mouse MSP1E3D1-His, lyophilized protein mouse MSP1E3D1-His, lyophilized protein
Mouse membrane scaffold protein 1 E3 D1, N-terminal 6xHis-tagged, 2 mg lyophilized protein
Article number: 26552
Sales price: From €170.00 *
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