Cubipol Glycerol
Order number: 18711
Description
Welcome the new addition to our NativeMP™ Platform: The Cubipol Series.
The proprietary Cubipol backbone, developed in-house, condenses the positive effects of previously available backbones like SMA, DIBMA, and UltrasoluteTM Amphipol. This new development delivers a new multimodal copolymer backbone, making the Cubipol series the first commercially available next-generation copolymer with 4 available off-the-shelf modified variants.
It joins the Next Generation Copolymers AASTY and Ultrasolute™ Amphipol, making solubilization and stabilization of membrane proteins a simpler and more effective endeavor than ever before.
Screening is key to discovering the best copolymer to stabilize your membrane protein target. Try the copolymers individually or save time by screening once and identifying the best stabilizing copolymers for your specific application with our NativeMP™ Screening Kit.
The proprietary Cubipol backbone, developed in-house, condenses the positive effects of previously available backbones like SMA, DIBMA, and UltrasoluteTM Amphipol. This new development delivers a new multimodal copolymer backbone, making the Cubipol series the first commercially available next-generation copolymer with 4 available off-the-shelf modified variants.
It joins the Next Generation Copolymers AASTY and Ultrasolute™ Amphipol, making solubilization and stabilization of membrane proteins a simpler and more effective endeavor than ever before.
Screening is key to discovering the best copolymer to stabilize your membrane protein target. Try the copolymers individually or save time by screening once and identifying the best stabilizing copolymers for your specific application with our NativeMP™ Screening Kit.
Cubipol Glycerol
This modification of the Cubipol backbone makes it one of the derivates with less charge like Sulfo-Cubipol and Glyco-Cubipol. The low charge makes it, so the copolymer does not interfere with charge-sensitive membrane protein processes like protein-protein and protein-lipid interactions.Because of its collective features (see Table below), this copolymer can be especially suited for charge sensitive downstream applications.
Datasheets
| Feature | |
|---|---|
| State | Lyophilized Powder, to be solved with water |
| Full Name | Cubipol Glycerol |
| Buffer | HEPES |
| pH after solving | 7.5 |
| pH Stability of Copolymer | 6.0-10 |
| Absorbance at 280nm | No |
| Molecular Weight | 10.7 kDA |
| Ca2+ tolerance | 10 mM |
| Mg2+ tolerance | 20 mM |
| Solubility | > 10% (H2O) |
| Polymerization Type | Free-Radical |
| Shipping Temperature | Ambient Temperature |
| Storage of lyophilized copolymer | -20°C for several years |
| Storage of dissolved copolymer | 2-8°C for several days |
Lab Results
Video
Watch this video and let Dr. Philipp Hanisch explain why you need to work with our NativeMP™ Copolymer Nanodiscs
Disclaimer
Patent Pending
The product described above has been developed and produced by Cube Biotech GmbH. Our products are intended for molecular applications. These products are not intended for diagnosis, prevention or treatment of a disease.
The product described above has been developed and produced by Cube Biotech GmbH. Our products are intended for molecular applications. These products are not intended for diagnosis, prevention or treatment of a disease.