R&D Target Pipeline

Working with complex proteins and drug targets like GPCRs and ion channels can be very challenging. These targets are crucial but notoriously difficult to handle, slowing down research and development progress. Another layer of complexity is added if you’re interested in the surrounding lipids, their interaction with the membrane protein, and physiological temperatures. From structural biology down to drug discovery, however, many of these targets offer a broad potential, as about half of all approved therapeutics target membrane proteins, and therefore set the foundation of modern scientific research.

R&D: NativeMPTM Targets

Explore the NativeMP target Portfolio:



Cube Biotech provides an extensive range of protein services tailored to the specific intricacies of both membrane proteins (GPCRs, transporters, ion channels, receptors etc.) and soluble proteins. This allows clinically relevant protein targets to be prepared, characterized, and interrogated with unprecedented efficiency, propelling client innovation and facilitating therapeutic discovery.
Fig. 1: Typical workflow of a novel drug target. Overarching area followed by more detailed steps Cube Biotech and partners can help you with to fast-track drug discovery.

Fast-track drug discovery with our friends and partners

Together with our scientific partners, we enable you to speed-up your drug discovery projects. Spanning from inital target identification and validation, over structure determination, and ending in hit identification and hit to lead (H2L) workflows, you can trust us to reach all the pre-clinical stages faster than usual. These partnerships, therefore, open up new fields of potential for you. Leverage novel high-throughput approaches for the interogation of highly clinically relevant membrane-bound proteins or start with the production of target specific antibodies. Everything is possible, with Cube Biotech and our partners.

The Pipeline

At Cube Biotech, we provide a comprehensive range of services for drug targets, including highly sought-after proteins like GLP1R and P2X4, available as off-the-shelf projects. For these projects we invested time and ressources to de-risk these high valuable targets so you can jump on the production pipeline at a much later point than starting from a novel target which hasn’t entered our screening platform yet. This saves you valuable time in getting the right protein in the right copolymer for your downstream application. Due to the uniqueness of our combinatorial approach of our vast portfolio of copolymers, each target is tailored to your application needs, be it protein assays or structural solution pipelines.

We are committed to delivering proteins in their most native form, ensuring the highest confidence in your drug discovery efforts. Discover our R&D target pipeline, showcasing proteins under close examination. Contact our Service Team to elevate your research with these critical drug targets. Experience the Cube Biotech difference and push the boundaries of scientific discovery and innovation.
Our expertise in synthetic copolymers allows us to offer:

The most native conditions on the market | Detailed protein-lipid interaction insights | Assays at physiological temperatures of 37°C

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Request a Target from our Pipeline!