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PMP22 / GAS3 - Peripheral myelin protein 22

Order number: 70921
PMP22 / GAS3 - Peripheral myelin protein 22

€12,800.00*

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Description

We are excited to introduce our off-the-shelf, full-length, active, and native Peripheral myelin protein 22, commonly known as PMP22. PMP22 might be involved in growth regulation, and in myelinization in the peripheral nervous system.

Our PMP22 protein has been solubilized and stabilized using our NativeMP™ platform, ensuring it retains its native structure and full biological activity, making it ideal for various research applications.

Applications:

  • Screening/Validation
  • Biologics Development
  • Structure Determination
  • Small Molecule Drug Development

The protein delivered can be used for these specific applications. When ordering, please indicate which applications you intend to use the protein for in the contact form to ensure the best results.

For more details, explore our solubilization database.

copolymer vs detergents workflow
Fig. 1: Detergents create environments that lack native lipids, which can compromise protein function and stability. Copolymers, enable you to see and analyze these aspects within a native environment. They facilitate studying how your target interacts with its surrounding lipids, and allow assays to be conducted at body temperature.

Datasheets

Upon ordering, you will receive the corresponding datasheets and the Certificate of Analysis (CoA).
Feature
Alternative namesGrowth arrest-specific protein 3 (GAS-3), PMP22
UniProt Number Q01453
Protein class Tetraspanin
Original host Homo sapiens
Expression system HEK293
Sequence, One-Letter Code MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKREGSSGTETSQVAPA
Affinity tags Rho1D4-tag (C-terminal)
Size (excluding additional elements) 160 amino acids, 19 kDa (Homodimer)
Concentration 0.4 - 0.7 mg/ml
Purity >90%, determined via SDS-PAGE
Purification process 2-step purification
Shipping Shipment is carried out on dry-ice for temperature stability to ensure the integrity of the product.
Function Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
PubMed ID 12107182

Citations

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