Pure & Active Membrane Proteins


Proteins active

Need pure, active, wild-type membrane proteins - in nanodiscs?

Membrane proteins, in particular GPCRs, are the most pharmaceutically relevant protein class. At the same time, it is very difficult to obtain them in pure, active form. Cube Biotech's protein experts have worked hard to produce human GPCRs and other membrane proteins in sufficient quality that we can now offer to the community. GPCRs are both available solubilized in detergent, or reconstituted into nanodiscs for stabilization.

colored membrane proteins
Colored membrane proteins are available that can be used as controls in protein crystallization, and biochemical/biophysical assays.
Whether you are planning to perform biophysical or biochemical experiments with the currently offered target proteins, or simply use them as positive controls to set up your targets of interest, we will be happy to discuss the quantities you need.

Pure & Active membrane proteins from Cube Biotech were successfully used in the following publications:

YearAuthorProduct
2022 Ritzmann N.1 Hs Bacteriorhodopsin



ProteinTarget NameOriginForm of solubilization / stabilization
GPBAR1/TGR5 G-protein coupled bile receptor 1 Human Detergent
GLP1R Glucagon-like peptide receptor 1 Human Detergent
NTSR1 Neurotensin receptor type 1 Human Detergent
VGT Vesicular glutamate transporter 2 Human  
BR Bacteriorhodopsin Halobacterium salinarum Detergent
HsSR-1 Sensory rhodopsin-1 Halobacterium salinarum Detergent
HsSR-2 Sensory rhodopsin-2 Halobacterium salinarum Detergent
NpSR-2 Sensory rhodopsin-2 Natronomonas pharaonis Detergent
CaChR1 Channelrhodopsin 1 Chloromonas augustae Detergent
MC4R Melanocortin receptor 4 Homo sapiens Detergent
AChR Acetylcholin receptor 1 Torpedo Californica  
 
Pure & Active Membrane Proteins
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Spike Protein Delta Variant SARS CoV-2 full-length Spike B.1.617.2 (Delta)...
Full-Length & active spike protein of the SARS-COV-2 mutant strain B.1.617,2, also known as the "Delta" mutant.
Article number: 28744
Sales price: From $309.60 *
Hs Bacteriorhodopsin Hs Bacteriorhodopsin
Active, purified purple membrane patches from Halobacterium salinarium. 5x 100 microgram in solution (500 µg). Shipped on dry ice - additional freight cost may apply.
Article number: 28903
Sales price: $534.00 *
AChR T. Californica AChR T. Californica
Native AChR from T.Californica, purified as funtional heterotetramer binding to Neurotoxin-3 ligand.
Article number: 28601
Sales price: From $758.40 *
SPIKE in LMNG Mycelle, product image SARS CoV-2 spike protein in LMNG detergent
The surface protein SPIKE of SARS-CoV-2 stabilized in LMNG detergent mycelles. Full-Length and in native trimeric form!
Article number: 28702
Sales price: From $904.80 *
GLP1R protein GLP1R protein
Active, purified membrane protein preparation. 10 microgram in solution. Shipped on dry ice - additional freight cost may apply.
Article number: 28201
Sales price: From $1,446.00 *
NTSR1 protein NTSR1 protein
Purified membrane protein preparation. 10 microgram in solution. Shipped on dry ice - additional freight cost may apply.
Article number: 28301
Sales price: From $1,302.00 *
Product Image SPIKE protein in DIBMA SARS CoV-2 spike protein in DIBMA Glycerol
The surface protein SPIKE of SARS-CoV-2 stabilized in synthetic nanodisc. Full-Length and in native trimeric form!
Article number: 28706
Sales price: From $1,183.20 *
SARS-CoV-2 spike protein in SMALP 200 (25µg) SARS-CoV-2 spike protein in SMALP 200 (25µg)
The coronavirus protein "spike" stabilized in a SMALP based nanodiscs. Full-length & active for your research.
Article number: 28715
Sales price: $1,183.20 *
Vial of 25 µg of Omicron Spike protein SARS CoV-2 full-length Spike B.1.1.529 /...
Full-Length & active spike protein of the SARS-COV-2 mutant strain B.1.1.529, also known as the "Omicron" mutant.
Article number: 28750
Sales price: From $309.60 *
GPBAR1 (TGR5) protein GPBAR1 (TGR5) protein
Active, purified membrane protein GPBAR1 (TGR1) from human. 10 or 50 µg in solution. Ready to ship and use for your research.
Article number: 28101
Sales price: From $1,446.00 *
MC4R protein MC4R protein
A membrane-bound receptor and member of the melanocortin receptor family. Pure & active it is ready for your research.
Article number: 28401
Sales price: From $1,302.00 *
Hs Sensory rhodopsin-1 Hs Sensory rhodopsin-1
Active, purified his-tagged membrane protein from Halobacterium salinarium. 100 microgram in solution. Shipped on dry ice - additional freight cost may apply.
Article number: 28911
Sales price: $427.20 *
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