DIBMA 6
Order number: 18751
Description
This new version of the classical DIBMAs 10 and 12 differs in its size and synthetization process.
The new DIBMA 6 is not only smaller than its predecessors (DIBMA 10 and DIBMA 12) but, together with Sulfo-DIBMA, belongs to a new generation of DIBMA’s that are RAFT polymerized. This achieves a reduction in both monomer size and lower polydispersity, meaning that if you need your copolymers to all have a similar size this is the copolymer to choose.
With DIBMA 6 you can directly extract membrane proteins from cells without an intermediate step of detergent solubilization, like with SDS which would usually interfere with your target protein's function. Another advantage of DIBMA 6 is the lack of an absorbance maxima at 280 nm. SMAs, in comparison, usually interfere with protein quantification, as aromatic amino acids absorb at the same spectrum.
The new DIBMA 6 is not only smaller than its predecessors (DIBMA 10 and DIBMA 12) but, together with Sulfo-DIBMA, belongs to a new generation of DIBMA’s that are RAFT polymerized. This achieves a reduction in both monomer size and lower polydispersity, meaning that if you need your copolymers to all have a similar size this is the copolymer to choose.
With DIBMA 6 you can directly extract membrane proteins from cells without an intermediate step of detergent solubilization, like with SDS which would usually interfere with your target protein's function. Another advantage of DIBMA 6 is the lack of an absorbance maxima at 280 nm. SMAs, in comparison, usually interfere with protein quantification, as aromatic amino acids absorb at the same spectrum.
See our biotinylated DIBMA 6 Biotin or find more of our biotinylated copolymers included in the NativeMP™ Biotin Kit.
Datasheets
| Feature | |
|---|---|
| State | Lyophilized Powder, to be solved with water |
| Full Name | Diisobutylene Maleic Acid in 50 mM HEPES, pH 7.5 |
| Buffer | HEPES |
| pH after solving | 7.5 |
| pH Stability of Copolymer | 5.0-10 |
| Absorbance at 280nm | No |
| Molecular Weight | 6 kDA |
| Ca2+ tolerance | 40 mM |
| Mg2+ tolerance | 50 mM |
| Solubility | > 10% (H2O) |
| Polymerization Type | RAFT |
| Shipping Temperature | Ambient Temparature |
| Storage of lyophilized copolymer | -20°C for several years |
| Storage of dissolved copolymer | 2-8°C for several days |
Citations
Influence of DIBMA Copolymer Length on Lipid Nanodisc Formation and Membrane Protein Extraction
Lab Results
Video
Watch this video and let Dr. Philipp Hanisch explain why you need to work with our NativeMP™ Copolymer Nanodiscs
Disclaimer
Patent Pending
Our products are intended for molecular applications. These products are not intended for diagnosis, prevention or treatment of a disease.
Our products are intended for molecular applications. These products are not intended for diagnosis, prevention or treatment of a disease.