Sulfo-Cubipol
Order number: 18721
Description
Welcome the new addition to our NativeMP™ Platform: The Cubipol Series.
The proprietary Cubipol backbone, developed in-house, condenses the positive effects of previously available backbones like SMA, DIBMA, and Ultrasolute™ Amphipol. This new development delivers a new multimodal copolymer backbone, making the Cubipol series the first commercially available next-generation copolymer with 4 available off-the-shelf modified variants.
It joins the Next Generation Copolymers AASTY and Ultrasolute™ Amphipol, making solubilization and stabilization of membrane proteins a simpler and more effective endeavor than ever before.
Screening is key to discovering the best copolymer to stabilize your membrane protein target. Try the copolymers individually or save time by screening once and identifying the best stabilizing copolymers for your specific application with our NativeMP™ Screening Kit.
The proprietary Cubipol backbone, developed in-house, condenses the positive effects of previously available backbones like SMA, DIBMA, and Ultrasolute™ Amphipol. This new development delivers a new multimodal copolymer backbone, making the Cubipol series the first commercially available next-generation copolymer with 4 available off-the-shelf modified variants.
It joins the Next Generation Copolymers AASTY and Ultrasolute™ Amphipol, making solubilization and stabilization of membrane proteins a simpler and more effective endeavor than ever before.
Screening is key to discovering the best copolymer to stabilize your membrane protein target. Try the copolymers individually or save time by screening once and identifying the best stabilizing copolymers for your specific application with our NativeMP™ Screening Kit.
Sulfo-Cubipol
The low charged, zwitterionic copolymer variation resembles softer surfactants with a high resistance to extreme pH values, ionic strength and divalent ion concentrations (details in the table below). It belongs to the Cubipol class with low charge, which allows for the uninterrupted study of charge-sensitive interactions between membrane proteins and lipids.See our biotinylated Sulfo-Cubipol variant included in the NativeMP™ Biotin Kit.
Datasheets
| Feature | |
|---|---|
| State | Lyophilized Powder, to be solved with water |
| Full Name | Sulfo-Cubipol |
| Buffer | HEPES |
| pH after solving | 7.5 |
| pH Stability of Copolymer | 5.5-10 |
| Absorbance at 280nm | No |
| Molecular Weight | 13.7 kDA |
| Ca2+ tolerance | 75 mM |
| Mg2+ tolerance | 100 mM |
| Solubility | > 10% (H2O) |
| Polymerization Type | Free-Radical |
| Shipping Temperature | Ambient Temparature |
| Storage of lyophilized copolymer | -20°C for several years |
| Storage of dissolved copolymer | 2-8°C for several days |
Lab Results
Video
Watch this video and let Dr. Philipp Hanisch explain why you need to work with our NativeMP™ Copolymer Nanodiscs
Disclaimer
Patent Pending
The product described above has been developed and produced by Cube Biotech GmbH. Our products are intended for molecular applications. These products are not intended for diagnosis, prevention or treatment of a disease.
The product described above has been developed and produced by Cube Biotech GmbH. Our products are intended for molecular applications. These products are not intended for diagnosis, prevention or treatment of a disease.