Nanodisc products ►Protein research | Cube Biotech

Nanodisc products


Nanodisc

Nanodiscs provide an exciting alternative for the stabilization of membrane proteins. Cube Biotech offers everything you need to get started with this novel technology. There are two options to reconstitute membrane proteins into nanodiscs:

For the reconstitution of membrane proteins that are already isolated and solubilized in detergent, we recommend to use membrane scaffold proteins (MSPs) in combination with phospholipids. A variety of membrane scaffold proteins (MSPs) are available that can be assembled to nanodiscs of different sizes to accommodate proteins with varying numbers of transmembrane domains. His-tagged MSPs allow for easy detection of the nanodisc and even immobilization on SPR chips. On the other hand, if the protein of interest itself carries a his-tag, we recommend to use untagged MSP proteins. For use in cell-free expression reactions, empty nanodiscs are recommended. They can be assembled using our Nanodisc assembly kits, or purchased ready to use. Note that these kits only provide small amounts of nanodisc that are suitable for cell-free expression, and not recommended for direct reconstitution of already purified proteins.

What our customers say:

Nanodisc Janssen  Testimonial
Cube Biotech ProductUsage
Lyophilized membrane scaffold proteins for reconstitution of purified proteins
Assembled nanodiscs For cell-free reactions
Assembly kits Prepare your own nanodiscs for cell-free reactions
Full nanodisc service from gene to protein Contact us! We will help you with your project.
Nanodisc

Nanodiscs provide an exciting alternative for the stabilization of membrane proteins. Cube Biotech offers everything you need to get started with this novel technology. There are two options to reconstitute membrane proteins into nanodiscs:

For the reconstitution of membrane proteins that are already isolated and solubilized in detergent, we recommend to use membrane scaffold proteins (MSPs) in combination with phospholipids. A variety of membrane scaffold proteins (MSPs) are available that can be assembled to nanodiscs of different sizes to accommodate proteins with varying numbers of transmembrane domains. His-tagged MSPs allow for easy detection of the nanodisc and even immobilization on SPR chips. On the other hand, if the protein of interest itself carries a his-tag, we recommend to use untagged MSP proteins. For use in cell-free expression reactions, empty nanodiscs are recommended. They can be assembled using our Nanodisc assembly kits, or purchased ready to use. Note that these kits only provide small amounts of nanodisc that are suitable for cell-free expression, and not recommended for direct reconstitution of already purified proteins.

What our customers say:

Nanodisc Janssen  Testimonial
Cube Biotech ProductUsage
Lyophilized membrane scaffold proteins for reconstitution of purified proteins
Assembled nanodiscs For cell-free reactions
Assembly kits Prepare your own nanodiscs for cell-free reactions
Full nanodisc service from gene to protein Contact us! We will help you with your project.
Nanodisc Products
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mouse MSP1E3D1-His, lyophilized protein mouse MSP1E3D1-His, lyophilized protein
Mouse membrane scaffold protein 1 E3 D1, N-terminal 6xHis-tagged, 2 mg lyophilized protein
Article number: 26552
Sales price: From €143.00 *
MSP1E3D1-His, lyophilized protein MSP1E3D1-His, lyophilized protein
Membrane scaffold protein 1 E3D1, N-terminal 6xHis-tagged, 2 mg lyophilized protein  
Article number: 26152
Sales price: From €124.00 *
MSP1D1-His, lyophilized protein MSP1D1-His, lyophilized protein
2 mg lyophilized membrane scaffold 1 D1 protein, his-tagged
Article number: 26112
Sales price: From €124.00 *
MSP1E3D1, lyophilized protein MSP1E3D1, lyophilized protein
Membrane scaffold protein 1 E3D1, His-tag removed by protease digest. 2 mg lyophilized protein
Article number: 26162
Sales price: From €238.00 *
Nanodisc MSP1D1-His_DMPC (50 µL) Nanodisc MSP1D1-His_DMPC (50 µL)
50 microliter pre-assembled nanodisc, 0.5 mM concentrated, containing MSP1D1-His protein and DMPC. For use in cell-free reactions only. Product is shipped on dry ice - additional freight charges apply.  
Article number: 26311
Sales price: €402.00 *
PureCube DIBMA 12, Screening Kit, 10x50 mg, TRIS PureCube DIBMA 12, Screening Kit, 10x50 mg, TRIS
PureCube DIBMA by Cube-Biotech. For protein solubilization. | Amount = 10X50mg | Buffered in TRIS. | MW=12.000 g/mol
Article number: 18014
Sales price: €175.00 *
Nanodisc MSP1D1_DMPC (50 µL) Nanodisc MSP1D1_DMPC (50 µL)
50 microliter pre-assembled nanodisc, 0.5 mM concentrated, containing MSP1D1 protein and DMPC. For use in cell-free reactions only. Shipped on dry ice - additional freight cost apply.
Article number: 26331
Sales price: €526.00 *
mouse MSP1E3D1, lyophilized protein mouse MSP1E3D1, lyophilized protein
Membrane scaffolding protein MSP1E3D1 for nanodisc assembly. Creates scaffolding diameters of 12-14 nanometers. Lyophilized.
Article number: 26562
Sales price: From €259.00 *
MSP1D1, lyophilized protein MSP1D1, lyophilized protein
Membrane scaffold protein (MSP)1D1, His tag removed by proteolytic digest. 2 mg lyophilized protein
Article number: 26132
Sales price: From €238.00 *
Nanodisc Assembly Kit MSP1D1-His_POPC Nanodisc Assembly Kit MSP1D1-His_POPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1, N-terminal 6xHis-tagged, 3.58 mg...
Article number: 26213
Sales price: €240.00 *
Nanodisc Assembly Kit MSP1D1 dH5-His_POPC Nanodisc Assembly Kit MSP1D1 dH5-His_POPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1 delta H5 mutant, N-terminal 6xHis-tagged, 3.12 mg...
Article number: 26223
Sales price: €240.00 *
Nanodisc Assembly Kit MSP1E3D1-His_POPC Nanodisc Assembly Kit MSP1E3D1-His_POPC
Nanodisc assembly kit to prepare empty nanodiscs e.g. for assembly of nascent proteins in cell-free expression reactions. Kit contents: 2 mg lyophilized Membrane scaffold protein 1 D1E3, N-terminal 6xHis-tagged, 4.22 mg...
Article number: 26253
Sales price: €240.00 *
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